WEBVTT 00:00.179 --> 00:07.617 Ọ̀ bụ́ na ndị e gbara mgbochi site na teknụzụ "vaccine" mRNA bụ́ ụmụ ọ̀gụ̀gụ e gbanwere site na genetiki? 00:07.617 --> 00:11.843 Gịnị mere ọgwụ mgbochi a ji nwee ike ịgbasa n'ime mmiri ara ehi? 00:11.843 --> 00:20.988 Gịnị mere mmetọ DNA n'ime ọgwụ mgbochi ndị a ji nwee ike ibute ụdị kansa ọhụrụ ma ọ bụ ọbụna kansa turbo? 00:20.988 --> 00:30.559 Nọgide na-ege ntị ma chọpụta na mmemme na-esote ihe kpatara teknụzụ "ọgwụ mgbochi" dabere na mRNA ji dị ize ndụ nye mmadụ! 00:30.559 --> 00:36.549 N'afọ 2019, n'ọnọdụ mgbasa ọrịa coronavirus, ejiworo teknụzụ ọgwụ mgbochi ọhụrụ n'ahụ 00:36.549 --> 00:40.549 mmadụ maka oge mbụ: teknụzụ ọgwụ mgbochi mRNA. 00:40.549 --> 00:46.721 Ọ bụ ezie na n'oge ahụ, ndị dọkịta dọrọ aka ná ntị na a ga-eji teknụzụ ọhụrụ a mee nnwale n'ubi n'elu ụmụ 00:46.721 --> 00:52.921 mmadụ niile, n'enweghị ọmụmụ sayensị siri ike e mere tupu ya iji nyochaa ihe ga-esi na ya pụta! 00:52.921 --> 00:58.902 Taa, ihe fọrọ nke nta ka ọ bụrụ afọ anọ gachara ewebatara teknụzụ mgbochi ọrịa a, ihe fọrọ nke nta ka ọ bụrụ egwu 00:58.902 --> 01:03.162 niile gbasara nsonaazụ teknụzụ mRNA a, nwute, aghọwo eziokwu. 01:03.162 --> 01:12.191 Onye ọkà mmụta sayensị molekul Prof. Dr. Klaus Steger na Prof. Dr. Alexandra Henrion-Caude, ọkachamara n'ọhịa RNA na epigenetics 01:12.191 --> 01:21.038 , ejirila nchọpụta sayensị kacha ọhụrụ gbasara teknụzụ mgbochi ọrịa dabeere na mRNA chịkọtara n'akwụkwọ ntinye ozi. 01:21.038 --> 01:27.338 Aha ya bụ: Teknụzụ 'ọgwụ mgbochi' dabere na mRNA: Egwuregwu gwụsịrị! 01:27.338 --> 01:32.795 Tupu anyị kọwaa nke a nkenke maka gị, lee nkọwa ole na ole nke okwu. 01:32.795 --> 01:42.670 A naghịzi akpọ mgbochi coronavirus mRNA mgbochi, kama a na-akpọ ya teknụzụ mgbochi dabere na modRNA eji na mmadụ. 01:42.670 --> 01:51.608 modRNA, n'ihi na ọ bụ mRNA e mepụtara n'aka mmadụ nke a pụghị ịtụnyere ya na mRNA mmadụ dị n'ahụ. 01:51.608 --> 01:58.534 Dị ka ọkà mmụta sayensị ndụ Prof. Dr. Ulrike Kämmerer si kwuo, a gaghị akpọ mgbochi coronavirus ka ọ bụ mgbochi. 01:58.534 --> 02:02.428 Dọkịta Kämmerer kwuru ihe ndị a n'ajụjụ ọnụ: 02:02.428 --> 02:06.425 "Ọ bụghị ọgwụ mgbochi n'echiche ọdịnala, kama ọ bụ ụdị injinịa mkpụrụ ndụ ihe nketa." 02:06.425 --> 02:13.197 Ọ bụghịkwa ọgwụgwọ mkpụrụ ndụ, n'ihi na a naghị agwọ ihe ọ bụla; kama ọ bụ injinia mkpụrụ ndụ. 02:13.197 --> 02:22.755 Ọ bụ ngwa injinịa mkpụrụ ndụ ihe nketa, ma ebe ọ bụ na ọgwụ mgbochi n'eziokwu gụnyere itinye nje nwụrụ anwụ ma ọ bụ akụkụ ya, 02:22.755 --> 02:30.937 ya bụ protein nje, n'ahụ, enwere m ọnụọgụ kpọmkwem nke agaghịzi emepụta onwe ya n'ahụ ma mechaa bibie, hapụ 02:30.937 --> 02:36.063 naanị mmeghachi omume mgbochi ahụ, dịka a ga-esi kwuo. 02:36.063 --> 02:46.009 Ma ugbu a, ana m eme ka sel mmadụ mee dịka nje ndị a n'ime ferment, ya bụ, ka ha mụọla mgbochi ọrịa n'onwe ha tupu ha 02:46.009 --> 02:57.080 amata otú ọ ga-esi dị irè, ogologo oge ọ ga-adị, ma eleghị anya ọ ga-adịru ndụ niile, ma ọ ga-abanye n'ime nuklia sel. 02:57.080 --> 03:03.667 Nke a pụtara na onye ọ bụla natara ọgwụ mgbochi ndị a, gụnyere ọgwụ mgbochi ndị ga-abịa n'ọdịnihu, ga-abụ, na mbido, ụmụ 03:03.667 --> 03:07.473 ọmụmụ e gbanwere mkpụrụ ndụ ihe nketa n'enweghị nkwenye ha. 03:07.473 --> 03:11.163 N'okpuru bụ nchịkọta mkpirikpi nke nsonaazụ ọmụmụ. 03:11.163 --> 03:16.913 teknụzụ mRNA n'ụdị mgbochi ọrịa nwere ike ibute ihe ndị a n'ahụ mmadụ: 03:16.913 --> 03:23.982 Mmụba ọkụ na-adịgide adịgide n'akụkụ niile nke ahụ, dịka ọmụmaatụ, mmụba ọkụ n'akwara obi na perikardium. 03:23.982 --> 03:28.280 A pụrụ ijikọta modRNA na DNA nke sel mmadụ. 03:28.280 --> 03:35.123 Ọ bụrụ na nke a mere na mkpụrụ ndụ mkpụrụ nwoke ma ọ bụ mkpụrụ ndụ mkpụrụ nwanyị, a ga-agbanwe genome nke ọgbọ ndị ga-abịa. 03:35.123 --> 03:43.762 Teknụzụ mgbochi ọrịa ModRNA ma ọ bụ itinye ModRNA n'ime sel nke ahụ n'onwe ya nwere ike ibute ụdị kansa ọhụrụ, ma 03:43.762 --> 03:49.240 n'ime ndị nwere kansa, ọ nwekwara ike ibute turbo kansa! 03:49.240 --> 03:55.154 Kla.TV ejirila mkpokọta isi okwu ole na ole si na akwụkwọ mgbasa ozi wee meegharịa ha ebe a n'ụdị mkpụmkpụ. 03:55.154 --> 04:02.079 Akwụkwọ ntuziaka zuru ezu dị n'okpuru mmemme ahụ na German na Bekee n'ime igbe anụnụ anụnụ. 04:02.079 --> 04:09.636 1. A gwara gị, "Ọ bụ ọgwụ mgbochi ọrịa," ma nke ahụ abụghị eziokwu. 04:09.636 --> 04:15.336 Ọ bụghị "ọgwụ mgbochi" n'ihi na ọ zutere ihe niile achọrọ maka ngwaahịa e mepụtara site na injinịa mkpụrụ ndụ. 04:15.336 --> 04:22.301 Ọ nwere mRNA emelitere e mepụtara site n'aka mmadụ, a na-akpọ ya modRNA, nke a kpuchiri n'ime 04:22.301 --> 04:27.735 nanoparticles abụba na-ebuga modRNA n'ime sel anyị. 04:27.735 --> 04:35.176 2. A gwara gị, "Ọ bụ mRNA," ma nke ahụ abụghị eziokwu. 04:35.176 --> 04:41.574 Ọ bụghị mRNA, kama ọ bụ mRNA gbanwere, modRNA. 04:41.574 --> 04:49.770 Ọ bụ ezie na modRNA a mepụtara site n'aka mmadụ na-eme ka ọ dị ka mRNA eke, ọ nwere njirimara kpamkpam dị iche: 04:49.770 --> 04:57.120 N'adịghị ka mRNA eke, nke na-efunahụ ngwa ngwa, achọpụtara modRNA sitere na "ọgwụ mgbochi" Covid-19 04:57.120 --> 05:02.387 n'ọbara ruo ụbọchị 28 na n'akụkụ anụ ahụ ruo izu asatọ. 05:02.387 --> 05:10.278 E gosiri na protein spike nke mRNA etinyere mepụtara na-agagharị n'ọbara ruo ọnwa isii. 05:10.278 --> 05:14.649 DNA dịkwa na mgbochi ọrịa, nke a kpamkpam na-atụghị anya ya. 05:14.649 --> 05:21.447 E chọtara nnukwu ọnụọgụ mmetọ DNA n'ime ngwugwu ọgwụ mgbochi, mmetụta ha na-akpata nchegbu 05:21.447 --> 05:26.247 dịka ihe ọmụma sayensị anyị dị ugbu a si kwuo. 05:26.247 --> 05:32.993 Ha nwere ike ibute mgbanwe n'ịchịkwa ọrụ mkpụrụ ndụ ma mee ka e nwee ihe ize ndụ nke ijikọta ha n'ime mkpụrụ ndụ ihe nketa anyị . 05:32.993 --> 05:41.427 3. A gwara gị: "Ụgwọ mgbochi ahụ na-anọgide n'ime akwara gị," ma nke ahụ abụghị eziokwu. 05:41.427 --> 05:49.695 A naghị atụ anya ka "ọgwụ mgbochi" nọgide n'akwara, kama ọ ga-abanye n'ọbara, n'akụkụ lymph na ọbụna n'ọmụ mmiri ara ehi. 05:49.695 --> 05:58.773 N'adịghị ka mkpụrụ ndụ dị na ọgwụ mgbochi ọdịnala, mkpụrụ nanoparticle abụba nke nwere mRNA anaghị anọgide n'ọbara. 05:58.773 --> 06:06.985 Kama nke ahụ, n'echiche, ha nwere ike ịbanye n'ime sel ọ bụla n'ahụ anyị, gụnyere akụkụ dị mkpa dịka obi, ụbụrụ, 06:06.985 --> 06:12.936 imeju, akpụkpọ afọ, iku ume, spleen, afọ, ovaries na testicles. 06:12.936 --> 06:17.561 Nanopartikulu abụba na-akpali ọkụ nke ukwuu ma na-egbu egbu. 06:17.561 --> 06:25.059 Ya mere, ịgba ọgwụ ugboro ugboro na-abawanye mmebi na sel anyị ma nwee ike iduga ọnwụ sel tupu oge eruo. 06:25.059 --> 06:31.152 Mmetụta ndị na-apụta ugboro ugboro ma dị njọ gụnyere myocarditis na pericarditis, ya bụ 06:31.152 --> 06:35.290 mgbakasị obi, karịsịa n'etiti ndị ntorobịa. 06:35.290 --> 06:41.290 O yikarịrị ka mgbakasị ahụ sitere na mwakpo autoimmune megide sel dị n'obi nke natara mkpụrụ 06:41.290 --> 06:45.839 e tinyere n'ahụ ma gosipụtara protein spike . 06:45.839 --> 06:55.266 5. A gwara gị na "mRNA apụghị ijikọta na DNA", ma nke ahụ abụghị eziokwu. 06:55.266 --> 07:03.469 mRNA sitere na "ọgwụ mgbochi" nwere ike ijikọta na DNA, n'ihi na e chọtara akụkụ nke usoro ya n'ime sel ọbara ndị ọrịa. 07:03.469 --> 07:11.055 Mmetọ DNA a chọtara na ọgwụ mgbochi mRNA nke BioNTech/Pfizer nwere usoro nje virus ọbọ nke gụnyere usoro 07:11.055 --> 07:19.028 promotọ Simian Virus 40 (SV40) , nke a maara na ọ na-akwalite mbufe DNA n'ime isi mkpụrụ ndụ. 07:19.028 --> 07:26.034 Nke a na-eme ka ihe ize ndụ dị elu na DNA mba ọzọ a ga-etinye n'ime genome nke sel anyị, na nsonaazụ a na-apụghị ịtụ anya ya. 07:26.034 --> 07:32.553 Ọ bụrụ na otu n'ime ihe ndị a mere na mkpụrụ ndụ mkpụrụ nwoke ma ọ bụ nwanyị nke na-etinye aka na ịtụ nwa, ọ 07:32.553 --> 07:36.698 ga-agbanwekwa mkpụrụ ndụ ihe nketa mmadụ nke nwa ahụ. 07:36.698 --> 07:43.544 Njikọta ọ bụla nke usoro sitere na "ọgwụ mgbochi" n'ime genome nwere ike ibute mmepụta nke mkpụrụ ndụ ihe 07:43.544 --> 07:48.069 nketa ọbịa na njikwa mkpụrụ ndụ ihe nketa na-ezighi ezi. 07:48.069 --> 07:57.366 Nke ikpeazụ nwere ike iduga n'ịrụ ọrụ oncogenes ma ọ bụ n'ịkwụsị ọrụ tumour suppressor genes , nke abụọ ahụ na-akwalite kansa. 07:57.366 --> 08:04.598 Ihe ize ndụ a na-akawanye njọ site na mmebi mgbochi ọrịa a hụrụ n'ọtụtụ ndị "tọrọ mgbochi", nke pụtara na 08:04.598 --> 08:13.488 nchebe mgbochi ahụ adịghị ezu megide mkpụrụ ndụ kansa. Nsonaazụ ya nwere ike ịbụ "turbo kansa". 08:13.488 --> 08:19.853 Ndị Ọkpara na Ndị Nwanyị, Nchọpụta sayensị gbasara teknụzụ mgbochi ọrịa mRNA nke dị n'akwụkwọ ntuziaka 08:19.853 --> 08:24.198 a dị n'ụwa niile ma enwere ike ịnweta ya n'ịntanetị. 08:24.198 --> 08:29.076 Otú ọ dị, ndị ọchịchị na-achịkwa na mgbasa ozi bụ isi adịghị njikere ijide nsogbu a! 08:29.076 --> 08:37.341 Ya mere, jiri kọntaktị onwe gị kesaa ọdụ a gbasara teknụzụ mgbochi ọrịa dabere na mRNA ka o kwe omume!