1 00:00:00,179 --> 00:00:07,617 Na batho ba entetsoeng ka theknoloji ea "ente" ea mRNA ke lihloloa tse fetotsoeng liphatsa tsa lefutso? 2 00:00:07,617 --> 00:00:11,843 Ke hobaneng ha ente ena e ka kena lebeseng la letsoele? 3 00:00:11,843 --> 00:00:16,954 Mme ke hobaneng ha tshilafalo ya DNA ka hara meento ena e ka baka mefuta e metjha ya 4 00:00:16,954 --> 00:00:20,988 mofetshe kapa esita le mofetshe o matlafaletseng? 5 00:00:20,988 --> 00:00:26,535 Salang le rona 'me le fumane lenaneong le latelang hore na hobaneng theknoloji ea 6 00:00:26,535 --> 00:00:30,559 "ente" e thehiloeng ho mRNA e kotsi ho batho! 7 00:00:30,559 --> 00:00:36,696 Ka 2019, nakong ya sewa sa coronavirus, ho ile ha sebediswa theknoloji e ntjha ya ente ho batho 8 00:00:36,696 --> 00:00:40,549 ka lekgetlo la pele: theknoloji ya ente ya mRNA. 9 00:00:40,549 --> 00:00:46,510 Le mehleng eo, dingaka di ne di lemositse hore thekenoloji ena e ntjha e tla sebediswa ho etsa teko ya tshebetso 10 00:00:46,510 --> 00:00:52,921 hodima batho bohle, ho sa etswa diphuputso tsa mahlale tse tebileng esale pele ho lekola ditlamorao tsa yona! 11 00:00:52,921 --> 00:00:57,779 Kajeno, hoo e ka bang lilemo tse 'ne ka mor'a ho hlahisoa ha theknoloji ena ea ente, ka bomalimabe hoo e ka 12 00:00:57,779 --> 00:01:03,162 bang litšabo tsohle mabapi le litlamorao tsa theknoloji ena e thehiloeng ho mRNA li phethahetse. 13 00:01:03,162 --> 00:01:11,945 Setsebi sa baeloji ea li-molecule Prof. Dr. Klaus Steger le Prof. Dr. Alexandra Henrion-Caude, setsebi sa lekaleng la RNA le 14 00:01:11,945 --> 00:01:21,038 epigenetics , ba akarelitse liphuputso tsa morao-rao mabapi le theknoloji ea liente e thehiloeng ho mRNA pampitšaneng. 15 00:01:21,038 --> 00:01:27,338 Sehlooho ke: Theknoloji ea 'ente' e thehiloeng ho mRNA: Papali e felile! 16 00:01:27,338 --> 00:01:32,795 Pele re ka u akaretsetsa sena ka bokgutshwanyane, mona ke ditlhaloso tse mmalwa tsa mantswe. 17 00:01:32,795 --> 00:01:38,820 Mokento oa coronavirus oa mRNA ha o sa bitsoa mokento, empa o bitsoa theknoloji ea mokento 18 00:01:38,820 --> 00:01:42,670 e thehiloeng ho modRNA e sebelisoang ho batho. 19 00:01:42,670 --> 00:01:51,608 modRNA, hobane ke mRNA e entsoeng ka boenjiniere ba lefutso e ke keng ea bapisoa le mRNA ea batho 'meleng. 20 00:01:51,608 --> 00:01:58,534 Ho latela setsebi sa baeloji Prof. Dr. Ulrike Kämmerer, ente ea coronavirus ha ea lokela ho bitsoa ente. 21 00:01:58,534 --> 00:02:02,428 Ngaka Kämmerer o boletse tse latelang puisanong: 22 00:02:02,428 --> 00:02:06,425 "Ha se ente ka kutloisiso e tloaelehileng, empa ke mofuta oa boenjiniere ba liphatsa tsa lefutso." 23 00:02:06,425 --> 00:02:10,498 Hape ha se phekolo ea liphatsa tsa lefutso, hobane ha ho letho le phekoloang; ho e-na le 24 00:02:10,498 --> 00:02:13,197 hoo, ke boenjiniere ba liphatsa tsa lefutso. 25 00:02:13,197 --> 00:02:21,611 Ke ts'ebeliso ea boenjiniere ba liphatsa tsa lefutso, 'me le hoja ente ea sebele e kenyelletsa ho enta mookotaba o bolaoeng kapa 26 00:02:21,611 --> 00:02:28,580 karolo ea oona, ke hore, protheine ea mookotaba, 'na ke na le tekanyo e behiloeng e seng e sa khone ho ata 27 00:02:28,580 --> 00:02:36,063 'meleng 'me qetellong e a bolaoa, e siea feela karabelo ea 'mele ea ho itšireletsa, ha re ka rialo. 28 00:02:36,063 --> 00:02:43,703 Empa joale ke qobella lisele tsa batho ho sebetsa joaloka libaktheria tsena mofuteng, e leng hore, ho qala ka ho hlahisa 29 00:02:43,703 --> 00:02:50,127 liente ka botsona ntle le ho tseba hore na li tla sebetsa hakae, hore na li tla tšoarella nako e kae, hore na 30 00:02:50,127 --> 00:02:57,080 mohlomong li tla tšoarella bophelo bohle, kapa hore na li tla kena ka har'a khubu ea sele. 31 00:02:57,080 --> 00:03:03,550 Sena se bolela hore motho e mong le e mong ea amohelang liente tsena, ho kenyeletsoa le liente tsa kamoso, qalong e 32 00:03:03,550 --> 00:03:07,473 tla ba mehloli e fetotsoeng liphatsa tsa lefutso ka likhoka. 33 00:03:07,473 --> 00:03:11,163 Ka tlase ke kakaretso e khuts'oane ea liphetho tsa phuputso. 34 00:03:11,163 --> 00:03:16,913 Theknoloji ea mRNA ka sebopeho sa liente e ka baka tse latelang ho batho: 35 00:03:16,913 --> 00:03:23,982 Ho ruruha ho sa foleng karolong e 'ngoe le e 'ngoe ea 'mele, mohlala, ho ruruha ha mesifa ea pelo le pericardium. 36 00:03:23,982 --> 00:03:28,280 RNA e fetotsoeng e ka kopanngoa le DNA ea lisele tsa batho. 37 00:03:28,280 --> 00:03:35,123 Haeba sena se etsahala liseleng tsa peo tsa bonna kapa tsa botšehali, jenomo ea meloko e tlang e tla fetoloa. 38 00:03:35,123 --> 00:03:42,007 Theknoloji ea ente ea ModRNA kapa ho kenyeletsoa ha ModRNA liseleng tsa 'mele ka boeona ho ka baka mefuta e 39 00:03:42,007 --> 00:03:49,240 mecha ea mofetše, 'me ho batho ba seng ba na le mofetše, ho ka baka mofetše o matlafalitsoeng! 40 00:03:49,240 --> 00:03:55,154 Kla.TV e akaretsitse lintlha tse 'maloa tse tsoang pampitšaneng 'me e li hlahisitse hape mona ka mokhoa o khutsufalitsoeng. 41 00:03:55,154 --> 00:04:02,079 Pampitšana e feletseng e ka fumanoa ka tlas'a lenaneo ka Sejeremane le Senyesemane ka lebokoseng le leputsoa. 42 00:04:02,079 --> 00:04:09,636 1. U bolelloa, "Ke ente," empa seo ha se 'nete. 43 00:04:09,636 --> 00:04:15,336 Ha se "ente" hobane e fihlella litekanyetso tsohle tsa sehlahisoa se fetotsoeng liphatsa tsa lefutso. 44 00:04:15,336 --> 00:04:22,381 E na le mRNA e fetotsoeng e entsoeng ka maiketsetso, modRNA, e phuthetsoeng ka har'a likaroloana tse nyenyane 45 00:04:22,381 --> 00:04:27,735 tsa mafura tse tsamaisang modRNA ka har'a lisele tsa rona. 46 00:04:27,735 --> 00:04:35,176 2. U bolelloa, "Ke mRNA," empa seo ha se 'nete. 47 00:04:35,176 --> 00:04:41,574 Ha se mRNA, empa ke mRNA e fetotsoeng, modRNA. 48 00:04:41,574 --> 00:04:49,770 Leha modRNA ena e entsoeng ka maiketsetso e etsisa mRNA ea tlhaho, e na le litšobotsi tse fapaneng ka ho feletseng: 49 00:04:49,770 --> 00:04:57,342 Ho fapana le mRNA ea tlhaho, e senyehang kapele, modRNA o tsoang ho 'mekento' ea Covid-19 o fumanoe maling nako e ka fihlang ho 50 00:04:57,342 --> 00:05:02,387 matsatsi a 28 le liseleng nako e ka fihlang ho libeke tse robeli. 51 00:05:02,387 --> 00:05:06,946 Ho bontšitsoe hore protheine ea spike e hlahisoang ke mRNA e kentsoeng e ka potoloha maling 52 00:05:06,946 --> 00:05:10,278 nako e ka fihlang likhoeling tse tšeletseng. 53 00:05:10,278 --> 00:05:14,649 DNA e boetse e teng ka har'a liente, e leng ntho e sa lebelloang ho hang. 54 00:05:14,649 --> 00:05:21,572 Ho fumanoe litšila tse ngata tsa DNA meqolong ea liente, 'me litlamorao tsa tsona lia tšoenya 55 00:05:21,572 --> 00:05:26,247 ho latela tsebo ea rona ea saense ea hajoale. 56 00:05:26,247 --> 00:05:32,993 Li ka baka phetoho taolong ea liphatsa tsa lefutso 'me tsa beha kotsi ea ho kena ka har'a liphatsa tsa rona tsa lefutso . 57 00:05:32,993 --> 00:05:41,427 3. U bolelloa: "Mokento o lula mosifeng oa hau," empa seo ha se 'nete. 58 00:05:41,427 --> 00:05:49,695 "Mokento" ha o a ka wa rerelwa ho dula mesifeng, empa e le ho kena maling, ditshikeng tsa lymph le esita le lebeseng la letswele. 59 00:05:49,695 --> 00:05:54,765 Ho fapana le likaroloana tse ling tse ling tsa liente tse tloaelehileng, likaroloana tse 60 00:05:54,765 --> 00:05:58,773 nyenyane tsa mafura tse nang le mRNA ha li lule maling. 61 00:05:58,773 --> 00:06:05,406 Ho e-na le hoo, li ka khona, ka tšimoloho, ho kena seleng e 'ngoe le e 'ngoe 'meleng oa rona, ho kenyeletsa le 62 00:06:05,406 --> 00:06:12,936 litho tsa bohlokoa tse kang pelo, boko, sebete, liphio, matšoafo, lienye, mpa, li-ovary le li-testicle. 63 00:06:12,936 --> 00:06:17,561 Likaroloana tse nyenyane haholo tsa mafura li baka ho ruruha haholo ebile li na le chefo. 64 00:06:17,561 --> 00:06:25,059 Ka hona, liente tse pheta-phetoang li eketsa tšenyo liseleng tsa rona 'me li ka ba lebisa lefung la lisele pele ho nako. 65 00:06:25,059 --> 00:06:31,055 Litla-morao tse mpe tse atisang ho hlaha li kenyeletsa myocarditis le pericarditis, ke hore, 66 00:06:31,055 --> 00:06:35,290 ho ruruha ha pelo, haholoholo ho batho ba bacha. 67 00:06:35,290 --> 00:06:41,468 Ho ruruha hona ho ka etsahala hore ho bakwe ke tlhaselo ya sesole sa mmele se hlaselang disele tsa pelo tse nkileng dikarolwana 68 00:06:41,468 --> 00:06:45,839 tse kentweng ka ente mme tsa bontsha protheine ya spike . 69 00:06:45,839 --> 00:06:55,266 5. U bolelloa hore "mRNA e ke ke ea kopanngoa le DNA," empa seo ha se 'nete. 70 00:06:55,266 --> 00:07:03,469 mRNA e tsoang "mokentong" e ka kopanngoa le DNA, kaha karoloana ea eona e fumanoe liseleng tsa mali tsa bakuli. 71 00:07:03,469 --> 00:07:09,888 Ditsilafatsi tsa DNA tse fumanweng mekento ya mRNA ya BioNTech/Pfizer di na le tatellano ya vaerase ya dikgabo e 72 00:07:09,888 --> 00:07:14,759 kenyeletsang tatellano ya sehlohlelletsi sa Simian Virus 40 (SV40) , e tsejwang ka ho 73 00:07:14,759 --> 00:07:19,028 kgothaletsa phalliso ya DNA ka hare ho ntlha ya sela. 74 00:07:19,028 --> 00:07:26,034 Sena se eketsa kotsi ea hore DNA ena e tsoang kantle e kopanngoe le jenomeng ea lisele tsa rona, ka litlamorao tse sa lebelloang. 75 00:07:26,034 --> 00:07:32,057 Ha e 'ngoe ea liketsahalo tsena e etsahala liseleng tsa peo tsa monna kapa tsa mosali tse amehang ho 76 00:07:32,057 --> 00:07:36,698 nolofatsa, e tla boela e fetole jenomeng ea motho ea morutuoa. 77 00:07:36,698 --> 00:07:43,258 Kopanyo efe kapa efe ea tšebetso ea jenomo ea tatellano e tsoang "mokenteng" e ka 'na ea fella ka ho 78 00:07:43,258 --> 00:07:48,069 hlahisoa ha jini e sele le taolong e sa tloaelehang ea jini. 79 00:07:48,069 --> 00:07:53,243 Sena se ka qetella se lebisitse ho kenngweng tshebetsong ha li-oncogene kapa ho tima ha lijini tse 80 00:07:53,243 --> 00:07:57,366 thibelang lihlahala , tse ka bobeli li khothalletsang kankere. 81 00:07:57,366 --> 00:08:04,129 Kotsi ena e mpefatswa ke ho fokotseha ha sesole sa mmele sa ho itwanela se bonoang ho batho ba bangata ba "entilweng", e leng se 82 00:08:04,129 --> 00:08:08,515 bolelang hore tshireletso ya mmele ha e a lekana kgahlanong le disele tsa mofets'e. 83 00:08:08,515 --> 00:08:13,488 Sephetho e ka ba "mofets'e o potlakileng haholo". 84 00:08:13,488 --> 00:08:19,505 Bahlomphehi, diphuputso tsa mahlale mabapi le theknoloji ya ente ya mRNA e tsheheditseng pampitshana ena di 85 00:08:19,505 --> 00:08:24,198 fumaneha lefatsheng ka bophara mme di ka fihlelleha inthaneteng. 86 00:08:24,198 --> 00:08:29,076 Leha ho le jwalo, balaodi le mecha ya phatlalatso e ka sehloohong ha ba a itokisetsa ho sebetsana le taba ena! 87 00:08:29,076 --> 00:08:34,663 Ka hona, sebedisa dikgokahano tsa hao tsa botho mme o phatlalatsa temoso ena mabapi le thekenoloji ya ente e 88 00:08:34,663 --> 00:08:37,341 theilweng hodima mRNA ka pharalatsa kamoo ho ka kgonehang!