WEBVTT 00:00.134 --> 00:08.852 "Ụbọchị atọ gachara mgbe m nwetara mgbochi ọgbụ atọ nke COVID-19 na 17 Jenụwarị 2022, m dara n'amaghị ama, ma 00:08.852 --> 00:17.475 mgbe m biliri, uche m gbagwojuru kpamkpam, ụkwụ m enweghịzi ike ijide m. Enweghị m ike ịga ije ọzọ." 00:17.475 --> 00:24.991 "N'ime ndị e nyerela mgbochi, achọpụtara protein spike na mgbakasị anụ n'ọtụtụ akụkụ ahụ n'ime izu na 00:24.991 --> 00:33.364 ọbụna ọnwa mgbe etinyere ọgwụ mgbochi, nke jikọtara ya na ọrịa dị oke njọ ma na-emekarị ka ọnwụ." 00:33.364 --> 00:43.071 Ma kedu ka a ga-esi kọwaa mmepụta a na-adịgide adịgide nke protein e koodu na mRNA nke a na-atụghị anya ya? 00:43.071 --> 00:50.465 N'ikpeazụ afọ 2023, Kla.TV bipụtara akwụkwọ ozi mberede Prof. Dr. Sucharit Bhakdi banyere "ihe ize ndụ 00:50.465 --> 00:54.729 na-adịghị agwụ agwụ nke mgbochi ọrịa RNA" n'asụsụ dị iche iche. 00:55.806 --> 01:02.757 Ugbu a, na ngwụcha ọnwa Machị 2024, Prof. Dr. Sucharit Bhakdi, Prof. Karina Reiss na Dr. Michael Palmer 01:02.757 --> 01:10.104 bipụtara otu edemede nke nchọpụta ọhụrụ na-ekwenye ihe ịdọ aka ná ntị niile e mere n'oge ahụ. 01:10.104 --> 01:15.510 Ha na-akọwa n'ụzọ sayensị ziri ezi, ma n'ụzọ ndị mmadụ nkịtị nwere ike ịghọta, ihe kpatara a ji kwuo na 01:15.510 --> 01:19.357 mgbochi ọrịa mRNA bụ aghụghọ ma dị ize ndụ nke ukwuu. 01:19.357 --> 01:28.197 Isiokwu a e nyochachara nke ọma zuru oke maka ịkekọrịta ya na onye ọ bụla ka na-amaghị isiokwu a nke ọma. 01:28.197 --> 01:32.724 Enwere ike ịchọta ya dị ka faịlụ PDF n'okpuru mmemme a maka mbipụta. 01:32.724 --> 01:37.865 N'okpuru, Prof. Bhakdi na-agụ edemede ahụ n'olu maka gị. 01:37.865 --> 01:47.615 Mmetụta dị egwu nke ọnọdụ Prof. Bhakdi kọwara nwere ike inwe n'ahụ ndị metụtara ya, gosipụtara na akụkọ sochiri nke Lara. 01:47.615 --> 01:55.172 Ọ bụ otu n'ime ọtụtụ mmadụ ndị merụrụ ahụ site na mgbochi coronavirus, ọ na-akọ akụkọ mwute ya na nnọkọ mgbasa ozi 01:55.172 --> 02:00.849 MWGFD nke akpọrọ "Enyerela, emebiwo, jụrụ… ugbu a gịnị?" Prof. 02:04.268 --> 02:13.410 Ndị mmadụ ibe m. Ụmụnna mmadụ, enwere m ihe dị oke mkpa ịgwa unu. 02:13.410 --> 02:21.539 Ọ gbasara nchọpụta kacha ọhụrụ nke DNA n'ime ọgwụ mgbochi. 02:21.539 --> 02:30.580 Ugbu a, isiokwu mkparịta ụka bụ ihe kpatara ọgwụ mgbochi RNA ji bụrụ aghụghọ ma dịkwa ize ndụ nke ukwuu. 02:30.580 --> 02:38.860 Kromosom bụ akwụkwọ ndụ, nke nwere ntuziaka e dekọrọ na DNA maka mmepụta molekul protein. 02:38.860 --> 02:46.095 Ọ bụrụ na ọ dị mkpa, a meghere akwụkwọ kwesịrị ekwesị ma e mepụtara otu oyiri nke usoro esi nri a chọrọ. 02:46.095 --> 02:50.009 Nke a bụ mRNA. 02:50.009 --> 02:55.858 Ọ na-achịkwa mmepụta protein ahụ, mgbe ahụ a na-atụfu ya. 02:55.858 --> 03:05.185 Vaksin RNA yiri oyiri ndị a nke ndụ dị mkpụmkpụ nke ntuziaka dị na kromosom; ma ọ bụghị ka ha, ha 03:05.185 --> 03:10.841 na-akpata mmepụta protein ndị na-abụghị nke ahụ anyị. 03:10.841 --> 03:21.662 Kama nke ahụ, ha na-akpali mmepụta nke antijeni ndị mba ọzọ, dịka protein spike nke SARS-CoV-2. 03:21.662 --> 03:30.371 Ntinye ọ bụla nke mgbochi a na-eweta ihe karịrị otu ijeri oyiri (mRNA molecules). 03:30.371 --> 03:39.220 Mmepụta buru ibu nke mRNA ọgwụ mgbochi chọrọ ka e nwee DNA ntuziaka n'ọtụtụ buru ibu. 03:39.220 --> 03:41.439 Kedu ka e si eme nke a? 03:41.439 --> 03:47.162 Usoro eji edozi nsogbu a bụ nkume ntọala nke injinia mkpụrụ ndụ. 03:47.162 --> 03:54.197 Biliọnụ na tiriliọnụ oyiri nke ntụziaka DNA si na nje bacteria pụta. 03:54.197 --> 04:01.605 A na-echekwa usoro esi nri n'ime obere kromosom nje a na-akpọ plasmids. 04:01.605 --> 04:10.940 Selụ nje na-ekewa kwa nkeji iri abụọ, nke pụtara na ọnụọgụ selụ na-abawanye ugboro asatọ kwa elekere. 04:10.940 --> 04:19.929 N'ụzọ a, a pụrụ ịnakọta ọtụtụ puku bakteria site na mmiri e ji akọrọ ha n'ime ụbọchị ole na ole, ma sel 04:19.929 --> 04:25.215 bakteria ọ bụla ga-enwe ọtụtụ oyiri nke plasmid ahụ. 04:25.215 --> 04:27.988 Ọ dị mfe ijikwa plasmid. 04:27.988 --> 04:35.860 Enwere ike itinye usoro nri mba ọzọ, ya bụ, mkpụrụ ndụ ihe nketa na-ede protein nje, dịka ọmụmaatụ. 04:35.860 --> 04:47.639 Mgbe mmụba nje gasịrị, a na-anakọta plasmidi, a na-eji ha dị ka ihe nlere maka mmepụta oyiri mRNA. 04:47.639 --> 04:56.007 Molekyụl RNA mechara kpokọta n'ime obere mkpụrụ abụba a na-akpọ lipid nanoparticles (LNPs). 04:56.007 --> 05:04.729 Ihe ndị bụ isi nke LNP na-emepụta n'ụlọ ọrụ ma a maara na ha nwekwara mmetụta ọjọọ n'onwe ha. 05:04.729 --> 05:14.822 Ọzọkwa, a ka na-anwaleghị ọbụna n'ahụ mmadụ ngwakọta mmanụ pụrụ iche Pfizer/BioNTech na Moderna ji, tupu a nyere mgbochi 05:14.822 --> 05:20.413 ọrịa mRNA sitere n'aka ndị nrụpụta abụọ ahụ nkwenye mberede. 05:20.413 --> 05:26.674 Nke a na-eweta ihe ize ndụ ahụike a pụghị ịjụ ma kpamkpam na-adịghị mkpa. 05:26.674 --> 05:38.531 Ngwugwu LNP nke RNA na-echebe ya pụọ na mmebi, na-eme ka ọ ruo akụkụ niile nke ahụ site n'ọbara. 05:38.531 --> 05:44.520 N'ebe ahụ, LNPs na-eme dịka ịnyịnya Trojan. 05:44.520 --> 05:49.040 Ha na-etinye ha n'ime sel, a na-ahapụ mRNA. 05:49.040 --> 05:52.457 Nke a na-esochi mmepụta protein spike. 05:52.457 --> 06:03.180 Nke a na-akpalite nzaghachi mgbochi ahụ, gụnyere mmepụta nke antibọdị pụrụ iche e mere iji chebe anyị pụọ na ọrịa n'ọdịnihu. 06:03.180 --> 06:09.954 Otú ọ dị, usoro mgbochi ọrịa na-amata ma bibie mkpụrụ ndụ ahụ na-emepụta protein ndị si mba ọzọ. 06:09.954 --> 06:15.467 N'ezie, nke a na-eme mgbe nje virus jidere mkpụrụ ndụ anyị. 06:15.467 --> 06:22.171 Ikike a ịmata protein ndị mba ọzọ dị ka ndị mba ọzọ adịlarị kemgbe a mụrụ ya. 06:22.171 --> 06:29.736 Ọ na-echebe anyị n'oge ndụ anyị niile, n'ihi na a na-ewepụ sel ndị nje virus metụtara nke ọma n'ụzọ a. 06:29.736 --> 06:31.900 Enweghị ike igbochi ya. 06:31.900 --> 06:41.803 Ya mere, mgbe e tinyere mRNA na-akọwa protein si mba ọzọ n'ime sel, sel ahụ na-emegbu site na usoro mgbochi ọrịa. 06:41.803 --> 06:48.040 Ịjụ akụkụ ahụ e gbanwere na-egosi eziokwu a bụ isi. 06:48.040 --> 06:52.145 Ọ bụrụ na ị nata akụrụ m, ị ga-ajụ ya. 06:52.145 --> 06:59.508 Ị nwetara akụrụ m nke abụọ, ma nzaghachi nke abụọ sochiri, naanị oge a ọ dị ngwa ma dịkwa iwe. 06:59.508 --> 07:09.685 Ihe ụkpụrụ ndị ahụ bụ isi na-akpata mmetụta ọjọọ na-arịwanye elu nke mgbọ ọgwụ mgbochi a na-emeghachi ugboro ugboro. 07:09.685 --> 07:19.740 Ọnụ ọgụgụ oyiri RNA e kpuchiri n'ime LNP nke a na-etinye na ọgwụ ọ bụla dị oke ukwuu. 07:19.740 --> 07:25.562 Ọtụtụ puku sel n'ahụ niile ga-awakpo site na usoro mgbochi ọrịa anyị. 07:25.562 --> 07:34.718 A ga-enwe ike igbochi mwakpo a naanị mgbe emechara mmepụta protein si mba ọzọ. 07:34.718 --> 07:37.632 Ma nke a ga-adịru ogologo oge ole? 07:37.632 --> 07:45.566 Ụbọchị ole na ole naanị, dịka ndị na-emepụta ọgwụ mgbochi na ndị ọchịchị na-ahụ maka iwu si kwuo ugboro ugboro? 07:45.566 --> 07:54.781 N'ime afọ abụọ gara aga, e mere nchọpụta na-akpata nchegbu nke na-adịghị kwekọrịta na nkwupụta a. 07:54.781 --> 08:02.835 N'ime ndị e nyerela ọgwụ mgbochi, achọpụtara protein spike na mgbakasị anụ n'ọtụtụ akụkụ ahụ n'ime izu ma ọ bụ 08:02.835 --> 08:10.649 ọbụna ọnwa mgbe etinyere ọgwụ ahụ , nke jikọtara ya na ọrịa siri ike ma na-emekarị ibute ọnwụ. 08:10.649 --> 08:19.700 Ma kedu ka a ga-esi kọwaa mmepụta a na-adịgide adịgide nke protein e koodu na mRNA nke a na-atụghị anya ya? 08:19.700 --> 08:30.139 Azịza a na-ekwe omume ma na-akpata nchegbu e nyere site na nchọpụta McKernan na ndị ọrụ 08:30.139 --> 08:36.372 ibe ya mere, nke ha bipụtara otu afọ gara aga. 08:36.372 --> 08:45.762 Anyị ekwuola na a na-emepụta mRNA site na ihe nlereanya DNA plasmid mgbe a na-emepụta ọgwụ mgbochi. 08:45.762 --> 08:54.214 Tupu a kpuchie mRNA n'ime LNP, a ga-ewepụ DNA a mbụ. 08:54.214 --> 09:03.558 Ma ọ bụghị ya, a pụrụ ijikọ DNA plazmid n'ime mkpụrụ abụba ọnụ na RNA. 09:03.558 --> 09:14.880 McKernan chọpụtara na a naghị eme nlezianya nzọụkwụ dị oke mkpa a nke iwepụ DNA plasmid. 09:14.880 --> 09:24.894 E chọtara oke DNA plazmid n'ọtụtụ ngwugwu ọgwụ mgbochi Pfizer na Moderna. 09:27.086 --> 09:34.145 A belatara nchọpụta Kevin McKernan site n'aka ọha mmadụ buru ibu. 09:34.145 --> 09:46.272 Ndị ọchịchị na-achịkwa iwu kwuru na ndị na-emepụta ihe gwara ha na e nwere DNA; otú ọ dị, nke a emeghị ka ha ghara inye 09:46.272 --> 09:52.920 nkwenye, n'ihi na uru ndị e kọrọ dị n'okpuru ókè WHO tọrọ. 09:52.920 --> 09:55.941 Ma ebee ka ókè ndị a si bịa? 09:55.941 --> 10:06.135 Ụlọ Ọrụ Ọgwụ Europe (EMA) tọrọ oke nke nanograms iri nke DNA maka dose ọgwụ mgbochi ọ bụla. 10:06.135 --> 10:13.127 O kpọtụrụ akụkọ WHO nke afọ 1998. 10:13.127 --> 10:22.316 Akụkọ nka a na-ekwu: "Dabere na ihe ọmụma dị ugbu a, DNA sitere na ahịrị sel na-aga n'ihu ruo 10ng kwa dose a 10:22.316 --> 10:27.936 kpochapụrụ ugbu a nwere ike ịtụle ya dị ka nke a nabatara." 10:27.936 --> 10:42.061 Oke elu ọhụrụ a anaghị etinye na ngwaahịa sitere na mkpụrụ ndụ nje, ahịrị mkpụrụ ndụ diploid ma ọ bụ ọkụzụ mkpụrụ ndụ mbụ. 10:42.061 --> 10:47.704 Anyị hụrụ na akụkọ WHO na-ekewa ụdị DNA abụọ. 10:47.704 --> 10:55.760 A na-ewere otu ka ize ndụ karịa nke ọzọ, ya mere a na-ejedebe ọnụọgụ ha na uru e kwuru. 10:55.760 --> 11:08.079 Ma n'ime ụdị abụọ ahụ, DNA plazmid dị n'ime ọgwụ mgbochi mRNA bụ nke dị ize ndụ karị ma ọ bụ nke dị ize ndụ pere mpe? 11:08.079 --> 11:19.088 Ọ bụghị n'eziokwu nke otu n'ime ụdị abụọ ahụ, n'ihi na ntuziaka WHO na-atụle n'echiche na DNA ọ bụla dị n'ime ọgwụ ma ọ bụ 11:19.088 --> 11:29.880 mgbochi ọrịa abụghị ihe ọzọ karịa: "DNA na-enweghị mkpuchi," nke ntinye ya n'ime sel ahụ anyị ga-adịghị arụ ọrụ nke ọma. 11:29.880 --> 11:42.794 N'aka nke ọzọ, DNA na-emebi dị n'ime mgbochi ahụ ga-enweta nkwakọ LNP, dịka mRNA si dị. 11:42.794 --> 11:49.960 Nkwakọ a na-eme ka ntinye DNA n'ime sel ahụ anyị rụọ ọrụ nke ọma karị . 11:49.960 --> 12:01.510 Ya mere, ọ ga-adị mkpa ịtọ ókè 'nchebe' maka DNA e kpuchiri na LNP site n'iji nnwale ọhụrụ a haziri nke ọma. 12:01.510 --> 12:07.479 Ma ka anyị were na ókè EMA tọrọ dị mma. 12:07.479 --> 12:10.860 Ebee ka nke a na-eduga anyị? 12:10.860 --> 12:18.923 N'akụkọ ya e kwuru n'elu , EMA na-ekwu na ihe nlereanya ọgwụ mgbochi niile ọ nwetara site na 12:18.923 --> 12:25.175 Pfizer/BioNTech tupu nkwenye kwekọrọ na oke EMA maka DNA fọdụrụ. 12:25.175 --> 12:32.981 Otú ọ dị, o doro anya na EMA ekweghị ka e nwee nlekọta mma na-aga n'ihu mgbe e kwadoro ya, na nke a 12:32.981 --> 12:37.995 metụtara kwa ndị ọchịchị nchịkwa iwu niile n'ụwa. 12:37.995 --> 12:46.659 A pụrụ ịkọwa nke a site na nchọpụta Kevin McKernan, nke na-egosi na ọdịnaya DNA dị na ngwugwu ọgwụ 12:46.659 --> 12:53.021 mgbochi niile e nwalechara karịrị ókè WHO na EMA tọrọ. 12:54.556 --> 13:05.209 Nke a na-eduga anyị n'echiche ijuanya na-akpata ụjọ na a mepụtara ọgwụ mgbochi ndị a na-ebute ọdachi n'enweghị 13:05.209 --> 13:16.388 njikwa ọ bụla, na e tinyere ọgwụ mgbochi ndị ahụ n'ahụ narị nde mmadụ, nke mebiri kpamkpam ọnọdụ nkwenye. 13:16.388 --> 13:25.878 Ugbu a, a machibidoro itinye ọgwụ nke na-ezuteghị nkọwa e depụtara na ikike ire ahịa. 13:25.878 --> 13:33.085 Ya mere, ịga n'ihu itinye mgbochi ọrịa ndị a abụghị ihe ọzọ ma e wezụga mpụ. 13:33.085 --> 13:47.488 Nke a bụ otú gọọmentị anyị si ruo ebe a n'amaghị ihe ha dị njọ, na ha emeela nke a nye ndị obodo ha ma na-aga n'ihu ime ya. 13:47.488 --> 13:59.444 Cheta: Ndị ọchịchị metụtara na mba ndị ọdịda anyanwụ jụrụ n'ụzọ siri ike ịnyocha ma òtù McKernan nwere ike ịbụ eziokwu. 13:59.444 --> 14:06.715 Kama nke ahụ, ha na-eti mkpu n'otu olu: DNA agaghị ọbụna abanye n'ime sel. 14:06.715 --> 14:14.166 Ma ọ bụrụ na ọ mere, a ga-emebi ya ngwa ngwa ma bibie ya ebe ahụ. 14:14.166 --> 14:24.682 Na mgbakwunye, mkpụrụ ndụ sel kewara site na cytosol nke sel site n'ime akwa mkpuchi na-apụghị ịbanye, ya mere DNA si n'èzí agaghị 14:24.682 --> 14:31.336 enwe ike ịbanye n'ime mkpụrụ ndụ sel iji rụọ ọrụ ya ebe ahụ. 14:31.336 --> 14:41.420 Ihe ọma naanị banyere akụkọ a na-ewute bụ na ndị ọchịchị kwesịrị ibu ọrụ egosila onwe ha. 14:41.420 --> 14:47.567 Ha nọ n'ọnọdụ siri ike, nke a doro onye ọ bụla anya. 14:47.567 --> 14:56.818 Ụlọ ọrụ steeti doro anya na ha jikọtara aka na ndị mere mpụ a dị egwu. 14:56.818 --> 15:06.260 Nchọpụta McKernan ga-eme ka onye ọ bụla nwere ọbụna obere ihe ọmụma gbasara sayensị ndụ kpọọ ụda ịdọ aka ná ntị. 15:06.260 --> 15:14.740 O doro anya na DNA plazmid e kpuchiri na LNP ga-abanye n'ime sel anyị nke ọma. 15:14.740 --> 15:24.315 Mgbidi nuklia enweghị ike ichebe kromosom mgbe niile; ọ na-agbapụta n'oge nkewa mkpụrụ ndụ ọ bụla, ma DNA si 15:24.315 --> 15:30.600 n'èzí na-etinye n'ime nuklia ọhụrụ e kere nke mkpụrụ ndụ ụmụ. 15:30.600 --> 15:40.263 Nnata a naanị ya zuru oke iji kpalite mmepụta ogologo oge nke protein ndị e koodu – itinye ya 15:40.263 --> 15:46.528 n'ime DNA nke kromosom anyị adịghị mkpa maka nke a . 15:46.528 --> 15:54.920 N'aka nke ọzọ, ma ọ bụrụ na njikọta dị otú ahụ mee, ọ na-eweta ihe ize ndụ ndị ọzọ. 15:54.920 --> 16:02.620 E kwadoro nchọpụta McKernan kemgbe site n'aka ụlọ nyocha ndị ọzọ dị na United States na Canada. 16:02.620 --> 16:14.675 Ugbu a, anyị na-akọ banyere nnwale ndị ọzọ e mere site n'aka otu ndị nchọpụta German nwere ahụmahụ n'ọgbọ ọgwụ mgbochi BioNTech. 16:16.863 --> 16:27.250 Nsonaazụ mbụ: Dị ka mbụ, achọpụtara nnukwu DNA nje n'ime ngwugwu isii niile e nyochara. 16:27.250 --> 16:35.700 Ihe mkpụrụ ndụ ihe nketa niile McKernan chọtara na plasmidi gara aga e chọpụtarakwa ebe a. 16:35.700 --> 16:50.098 Nke a metụtara kwa ihe a na-akpọ promotọ SV40, ihe pụrụ iche nke e zoro ezo site n'ọha na eze na ndị ọchịchị na-achịkwa iwu. 16:50.098 --> 16:59.662 Gịnị mere Pfizer na BioNTech ji tinye promotọ SV40 n'ime plasmid ha bụ ajụjụ na-atọ ụtọ nke ukwuu. 16:59.662 --> 17:13.297 Ihe a adịghị mkpa maka mmepụta mRNA spike, ọ dịghịkwa na plasmidi Moderna ji emepụta ọgwụ mgbochi. 17:13.297 --> 17:24.140 Otú ọ dị, onye na-akwalite SV40 nwere ikike ijuanya ịbanye n'onwe ya na usoro DNA ejikọtara ya gafee akpụkpọ 17:24.140 --> 17:31.320 nuklia zuru oke, ọbụna n'ime sel ndị na-adịghị kewapụ ugbu a. 17:31.320 --> 17:38.031 Anyị hapụrụ ya n'aka gị ka ị chee ihe nke ahụ pụtara. 17:38.031 --> 17:46.533 Ajụjụ na-esote bụ: Ò nwere ike ka DNA plazmid banye n'ime sel mmadụ ma nọrọ ebe ahụ ogologo oge? 17:46.533 --> 17:49.502 Azịza bụ ee! 17:49.502 --> 17:59.371 Otu ndị nchọpụta chọpụtara na ntinye DNA na-eme ngwa ngwa, na ọ na-anọgide n'ime sel maka ọtụtụ ụbọchị mgbe e mesịrị, ka a ka 17:59.371 --> 18:05.024 na-enwe ike ịchọpụta ya ọbụna mgbe otu usoro nkewa sel gasịrị. 18:05.024 --> 18:12.580 Nkwupụta na a na-ebibi DNA a na-eri nri ngwa ngwa kpamkpam bụ ụgha – ọ bụkwa ozi ọgwụ 18:12.580 --> 18:18.138 na-ezighị ezi nke nwere ike ibute ihe ize ndụ. 18:20.636 --> 18:32.386 Ugbu a e nwere ọtụtụ ihe atụ ebe a tinye DNA mba ọzọ n'akwụkwọ ndụ, n'ime kromosom nke sel na nke anụmanụ ụlọ nyocha. 18:32.386 --> 18:36.600 Nsonaazụ ndị nwere ike ime dị iche iche ma a pụghị ịtụ anya ha. 18:36.600 --> 18:46.293 Mmejọ n'usoro a haziri nke ọma nke na-achịkwa nkewa na mmepe mkpụrụ ndụ nwere ike ibute kansa. 18:46.293 --> 18:53.650 Mgbanwe na mkpụrụ ndụ ihe nketa nke na-arụ ọrụ dịka akụkụ nke usoro mgbochi ọrịa nwere ike iduga n'ịrụghị ọrụ ya nke ọma. 18:53.650 --> 19:03.420 Mmebi nke mkpụrụ ndụ ihe nketa n'ime mkpụrụ ndụ ụbụrụ nwere ike ibute ọrịa ụbụrụ ọ bụla a pụrụ ichepụta. 19:03.420 --> 19:11.848 Ọ bụrụ na DNA si mba ọzọ tinye onwe ya n'ime kromosom nke mkpụrụ nwoke ma ọ bụ akwa a 19:11.848 --> 19:18.340 kụrụ, àgwà ndị gbanwere ga-adịrị n'ọgbọ na-esote. 19:18.340 --> 19:21.798 Nke a na-eduga anyị na ajụjụ ikpeazụ anyị: 19:24.732 --> 19:35.400 Anyị kwesịrị ichegbu onwe anyị na DNA nje sitere na mgbochi nwekwara ike itinye n'ime kromosom mmadụ? 19:35.400 --> 19:44.452 Iji dozie ajụjụ a, otu ndị Jamanị zitere Kevin ọkpụkpụ sel ha gwara ọgwụ mgbochi, 19:44.452 --> 19:50.849 na-arịọ ka e gụọ usoro DNA sel ndị ahụ kpamkpam. 19:50.849 --> 19:56.254 Enwere ike ịhụ nsonaazụ na Substack nke Kevin . 19:56.254 --> 20:00.620 Azịza ahụ bụ ọzọ: ee! 20:00.620 --> 20:11.267 Ihe àmà nke DNA nje n'ime kromosom nke sel ndị dị otú ahụ fọrọ nke nta ka ọ zuru ezu ugbu a. 20:11.267 --> 20:23.426 Ọ bụrụ na nke a na-eme na sel ndị dị iche iche, ọ̀ nwere ihe kpatara o ji apụghị ime na ahụ? 20:23.426 --> 20:29.112 Oge a, na naanị oge a, azịza anyị bụ mba. 20:29.112 --> 20:42.069 Taa, ebe a na ugbu a, anyị na-eche ihu nghọta na gọọmentị n'ụwa niile amalitela mmemme satani nke emebiwo ahụ, gbuo ọtụtụ nde 20:42.069 --> 20:49.760 mmadụ na-enweghị chioma n'ụwa niile ma gbanwee mkpụrụ ndụ ha. 20:49.760 --> 20:59.922 Ma a ga-eme ka mmemme a gbasaa; WHO chọrọ dochie mgbochi ọrịa ọdịnala n'ahụ mmadụ na n'ọgwụ 20:59.922 --> 21:06.227 anụmanụ na ngwugwu mgbanye mRNA n'akụkụ niile. 21:06.227 --> 21:15.492 Ụwa Ọha na Eze (WHO) na-agwa anyị na a gosipụtara nchekwa ọgwụ mgbochi COVID nke ọma nke ukwuu, nke mere na ọ dịghịzi mkpa 21:15.492 --> 21:21.568 ịnwale nke ọma ọgwụ mgbochi mRNA ndị ga-abịa megide nje ndị ọzọ. 21:21.568 --> 21:31.812 Ma ọ nweghị ihe dị anya na eziokwu karịa nkwupụta dara ogbenye a nke sayensị ọgwụgwọ. 21:31.812 --> 21:41.020 Ndi obodo m, maka uru gi na nke ndi i huru n'anya, ejula otu ihe a n'uche: 21:41.020 --> 21:51.795 Igosipụta antigen si mba ọzọ n'ime sel nke ahụ anyị ga-eduga mgbe niile ka usoro mgbochi ọrịa gbaa sel ahụ ọdụ. 21:51.795 --> 22:00.769 Ebe ọ bụ na ọgwụ mgbochi mRNA ọhụrụ ọ bụla na-emepụta antigen mba ọzọ nke ya, ọ bụla n'ime ha ga-akpata mmebi, 22:00.769 --> 22:10.000 dịka anyị hụrụ na ọgwụ mgbochi e mepụtara site na injinịa mkpụrụ ndụ ihe nketa megide COVID-19. 22:10.000 --> 22:17.609 Dị ka mbụ, mmebi a ga-esiwanye njọ n'oge ọ bụla a na-emegharị ya. 22:17.609 --> 22:29.966 Mmetọ nke mgbochi mRNA ga-adịkarịkwa, n'ihi na enweghị usoro dị ọnụ ala ma dịkwa ntụkwasị obi iji kewapụ mRNA e mepụtara 22:29.966 --> 22:43.051 n'ọtụtụ site na plasmid – ma n'ọnọdụ ọ bụla, ọ dị ka ọ nweghị onye na-enyocha ma a na-eso ụkpụrụ mmepụta ọ bụla. 22:43.051 --> 22:45.860 Mmemme WHO bụ ihe egwu nye mmadụ niile. 22:45.860 --> 22:49.346 Ọ na-eyi gị na ndị ị hụrụ n'anya egwu. 22:49.346 --> 22:56.453 Ndị mmadụ n'ụwa niile, jikọọ ọnụ ma zọpụta anyị n'ịgbagha ime mpụ a! 22:56.453 --> 23:03.890 Ka anyị kwụsị ọgwụ mgbochi mRNA – ka anyị kwụsị WHO! 23:13.921 --> 23:19.759 Ndewo, aha m bụ Lara, taa aga m ịgwa gị akụkọ m. 23:19.759 --> 23:21.290 Aha m bụ Lara. 23:21.290 --> 23:24.848 Aha m bụ Lara, ma otu ọnwa gara aga ka m ruru afọ iri abụọ. 23:24.848 --> 23:34.063 Aha m bụ Lara, afọ iri abụọ ka m dị, izu abụọ tupu m mee afọ iri na asatọ, n'otu oge ahụ ka m chọpụtara na enweghị m ike ịga ije. 23:34.063 --> 23:43.617 Ụbọchị atọ gachara mgbe m nwetara mgbochi ọrịa coronavirus nke atọ na 17 Jenụwarị 2022, m dara n'ala, ma mgbe 23:43.617 --> 23:52.431 m biliri, uche m jụrụ m kpamkpam, ụkwụ m enweghịzi ike ijide m. Enweghị m ike ịga ije ọzọ. 23:52.431 --> 23:55.931 Agaghị m echefu ụbọchị a n'oge na-adịghị anya. 23:55.931 --> 24:03.188 Mgbe otu awa gasịrị, amalitekwara m inwe nsogbu iku ume, e mesịrị ebuga m n'ụlọ ọgwụ ụmụaka. 24:03.188 --> 24:05.063 Ee 24:07.345 --> 24:12.260 N'oge sochirinụ, ọnọdụ m adịghị agbanwe nke ukwuu. 24:12.260 --> 24:15.758 Ọbụna aka m enweghị ike ijide ihe nke ọma. 24:15.758 --> 24:18.243 E ji m ụbọchị m niile nọ n'elu akwa. 24:18.243 --> 24:25.149 Ịgụ akwụkwọ adịghị ekwe omume n'ihi na mgbe m rutere n'okwu nke atọ n'ahịrịokwu ahụ, echefuru m okwu abụọ mbụ. 24:26.657 --> 24:30.092 Egwu na vidiyo mere ka m nwee enyi. 24:30.092 --> 24:35.217 A gbakwunyere incontinence n'ngwakọta, okwu ahụ amaghị m ọbụna. 24:35.217 --> 24:39.060 E jidere m n'elu akwa ruo ọnwa anọ. 24:39.060 --> 24:41.451 Mgbe ahụ ka m dị afọ iri na asatọ. 24:41.451 --> 24:48.120 Maka m, nke ahụ ga-abụ oge m ga-apụ, izute ndị enyi, ma nwee nnwere onwe m. 24:48.120 --> 24:51.273 Ma e jikọtara m n'akpa ụra. 24:51.273 --> 24:54.648 Enyi kwụsịrị ibe ha otu otu. 24:54.648 --> 25:02.408 N'aka otu, ọ na-ewute m nke ukwuu, ma n'aka nke ọzọ, gịnị ka ị ga-eme na onye na-anọ naanị n'ụlọ? 25:02.408 --> 25:06.135 Enweghị m ike ịkọwa onwe m ihe niile siri ike sochiri. 25:06.135 --> 25:08.593 Ọ ga-agafe oge a. 25:08.593 --> 25:12.197 Aga m kọwaa ya n'okwu igodo. 25:12.197 --> 25:15.619 Acupuncture mere ka m laghachite n'ụkwụ m. 25:15.619 --> 25:17.860 A na m emeghachi afọ n'ụlọ akwụkwọ. 25:17.860 --> 25:23.150 Enwere m ike ijikwa njem mkpirikpi abụọ, Paris na Rome. Ehee! 25:23.150 --> 25:29.096 Ma Septemba 2022... Agwụ ike dị ka ọla dị arọ na-amalite. 25:29.096 --> 25:31.330 Mbọghachi malitere. 25:31.330 --> 25:33.486 Enweghị m ike ịga ọzọ. 25:33.486 --> 25:37.273 Ana m agbalị imeghachi klas ahụ. Ọ naghị arụ ọrụ. 25:37.273 --> 25:39.391 Ịgbanwe ụdị ụlọ akwụkwọ, ọ dị mma. 25:39.391 --> 25:40.953 Enweghịzi kọleji ọkwa isii. 25:40.953 --> 25:42.740 Ma mgbanwe ahụ dị mma. 25:42.740 --> 25:48.462 Aga m enweta ọkpụkpọ ụkwụ ka m wee nwee ike ịga ụlọ akwụkwọ ọbụna n'ụbọchị ọjọọ. 25:48.462 --> 25:54.174 Oge nke ihe a na-akpọ mgbaghachi malitere. 25:54.174 --> 25:58.720 Ọkpụkpụ enyemaka ahụ adịghịzi enyere m n'ihi na agwụla m ike iji ha. 25:58.720 --> 26:04.727 A ghaghị m ịnakwere ihe m na-adịghị achọ mgbe niile: oche igwe. 26:04.727 --> 26:06.965 Ma m nwere ike ịga ụlọ akwụkwọ. 26:06.965 --> 26:10.987 Mgbe ahụ, e biri m n'ụdị usoro ịlaghachi azụ. 26:10.987 --> 26:14.404 Ugbu a amụrụ m ịbi ndụ na mmeghachi ndị a. 26:14.404 --> 26:20.075 Kemgbe ụbọchị ahụ n'ọnwa Jenụwarị afọ 2022, ndụ m dị ka ụgbọ elu na ala: 26:20.075 --> 26:26.948 Ịlaghachi azụ, nkwụsị, ịlaghachi azụ ntakịrị, nkwụsị, ịlaghachi azụ nke ukwuu, nkwụsị. 26:26.948 --> 26:31.335 Ọ bụghị mfe. Ma m nwere ike ime ya. Achọrọ m ime ya. 26:31.335 --> 26:33.862 Enwere m ọtụtụ nrọ. 26:33.862 --> 26:40.086 N'ime afọ abụọ a, echebara m ihe pụrụ iche banyere otu ihe nke nwere ike iyi na ọ bụghị ihe dị mkpa. 26:40.086 --> 26:42.134 Amaghị m ihe m nwere. 26:42.134 --> 26:43.959 Ọ dịghị onye maara. 26:43.959 --> 26:53.880 Echetara m ụbọchị nne m chọpụtara na Ịntanetị na ọrịa m na-enweghị aha n'ikpeazụ nwere aha: Post-Vac Syndrome, Post-Vac Syndrome. 26:53.880 --> 26:58.335 Ugbu a, enwere m ike ịse ọchị banyere ya. N'ihi na ọ bụghị n'eziokwu aha ọrịa. 26:58.335 --> 27:00.020 Ma obi dị m ụtọ. 27:00.020 --> 27:02.638 Ugbu a amaara m ihe mere o ji dị m ezigbo mkpa. 27:02.638 --> 27:08.300 N'ihi na mmadụ hụrụ m n'amaghị ama. Ma ọnọdụ m nwere aha. 27:08.300 --> 27:11.537 N'ihi na m kesara ndị ọzọ ọrịa m. 27:11.537 --> 27:13.312 Anọghị m naanị m ọzọ. 27:13.312 --> 27:15.946 Ma ọ bụ nnwere onwe. 27:15.946 --> 27:23.176 Mgbe ọtụtụ nnyocha gasịrị, nke na-agwụcha mgbe niile na "ihe niile dị mma," n'ikpeazụ e chọpụtara m 27:23.176 --> 27:27.934 ọrịa abụọ: ọrịa akwara eriri nta na ọrịa ike gwụrụ. 27:27.934 --> 27:34.200 N'ụzọ njem a dị ogologo, ọ bụghị naanị na m nwere ahụmịhe ọjọọ na nlekọta ahụike. 27:34.200 --> 27:36.580 Ụfọdụ dọkịta ole na ole kpebiri n'ụzọ doro anya. 27:36.580 --> 27:41.752 Ị nyere m aka ịga ntakịrị n'ihu, ma ekele m gị site n'ime obi m niile. 27:41.752 --> 27:43.873 Anọ m ka n'elu roller coaster. 27:43.873 --> 27:45.780 Ọ ka na-aga. 27:45.780 --> 27:47.700 Ma ọ ghọrọ larịị ugbu a. 27:47.700 --> 27:49.003 Enwere m olileanya na ọ ga-anọgide otu a. 27:49.003 --> 27:53.264 Ma olileanya m bụ na otu ụbọchị m ga-enwe ike ịhapụ ụgbọ elu na ala a kpamkpam. 27:53.264 --> 27:58.699 Ọ ga-adị mma ịkwụ n'ala na ụkwụ m na-arụ ọrụ. 27:58.699 --> 28:00.730 Gaa n'ihu na-eme nchọpụta! 28:00.730 --> 28:08.476 Anyị niile chọrọ nghọta. Ma achọrọ m gị. Daalụ. 28:11.867 --> 28:18.361 Òtù MWGFD emeela ajụjụ ọnụ ndị ọzọ na-adọrọ mmasị ma na-emetụ obi, na ndị mmadụ ndị merụrụ ahụ site na ọgwụ mgbochi 28:18.361 --> 28:22.273 mRNA, n'usoro akpọrọ "Tinyechara mgbochi, Merụrụ ahụ, Jụrụ". 28:22.273 --> 28:25.740 Ị nwere ike ịchọta ha n'okpuru njikọ e gosiri. 28:25.740 --> 28:32.792 Ebe a na-atụ anya itinye teknụzụ mRNA maka mgbochi ọrịa ndị ọzọ – ma ọ bụ, n'eziokwu, ọgwụgwọ mkpụrụ ndụ – ọ 28:32.792 --> 28:39.118 dịkwuo mkpa ka e kọọ akụkọ ndị a na-akpali akpali gbasara mmebi sitere na mgbochi ọrịa. 28:39.118 --> 28:42.797 Biko nwee onwe gị ịkekọrịta ajụjụ ọnụ ndị a. 28:42.797 --> 28:50.124 Ị nwekwara ike inyere aka igosipụta oke mmebi ọgwụ mgbochi mRNA kpatara site n'ịkọ mmebi ọ bụla nke 28:50.124 --> 28:54.120 ọgwụ mgbochi kpatara na mpaghara gị na vetopedia.org.