WEBVTT

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"Ezinsukwini ezintathu ngemva kokuthola umjovo wami wesithathu
we-COVID-19 ngomhlaka 17 Januwari 2022, ngagwegwaza, kwathi

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lapho ngivuka, ngangididekile ngokuphelele futhi imilenze
yami yayingasakwazi ukungiphatha. Angisakwazanga ukuhamba."

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"Kulabo ababegonyelwe, iphrotheni ye-spike nokuvuvukala
kwatholakala ezithweni eziningi emasontweni

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noma ezinyangeni ngemuva kokugonywa,
okuhlotshaniswa nezifo ezinzima futhi ezivame ukubulala."

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Kodwa-ke, lo mkhiqizo ongazelelwe nowokuqhubekayo
wephrotheni ebhalwe ku-mRNA ungachazwa kanjani?

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Ekupheleni kuka-2023, i-Kla.TV yashicilela incwadi
esheshayo kaProfesa Dr. Sucharit Bhakdi mayelana nezingozi

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ezingapheli zezitofu zokugoma ze-RNA ngezilimi eziningana.

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Manje, ekupheleni kukaMashi 2024, uProf. Dr. Sucharit Bhakdi,
uProf. Karina Reiss noDkt. Michael Palmer

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bashicilele indatshana lapho okutholakele okusha
kuqinisekisa zonke izixwayiso ezenziwe ngaleso sikhathi.

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Bachaza ngendlela yesayensi ecacile, kodwa ngendlela eqondakala
kalula kubantu abangochwepheshe kwezokwelapha, ukuthi kungani

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imijovo ebizwa nge-mRNA ingamanga futhi iyingozi kakhulu.

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Lesi sihloko esicwaningwe kahle silungele ukwabelana
ngaso nanoma ubani ongakaqondi lolu daba ngokujulile.

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Iyatholakala njengefayela le-PDF
ngaphansi kwale nkqubo yokuphrinta.

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Ngezansi, uProfesa Bhakdi ufunda le ndatshana ngawe.

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Umthelela omkhulu wezimo ezichazwe nguProfesa Bhakdi
kubantu asebethintekile ubonakala embikweni olandelayo kaLara.

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Ungomunye wama-victim angenakubalwa okubangelwa umjovo wokugoma
i-coronavirus futhi uxoxa indaba yakhe yobuhlungu

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emhlanganweni wezabezindaba we-MWGFD othi
"Sigomelwe, salimala, savinjwa... manje-ke yini?" Prof.

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Bantu abathandekayo. Mndeni wabantu, nginento
ebaluleke kakhulu engifuna ukukutshela yona.

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Kuyindaba yokutholakala kwakamuva kwe-DNA emajabini.

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Kungani imijovo yokugoma ye-RNA ingamanga futhi
iyingozi kakhulu manje isiyindaba yokuxoxwa ngayo.

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Ama-chromosome izincwadi zokuphila, aqukethe izindlela
zokupheka ezibhalwe nge-DNA zokukhiqiza ama-molecule ephrotheni.

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Uma kudingeka, ivulwa incwadi efanele
futhi kwenziwa ikhophi yeresiphi efunwayo.

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Le khopi iyi-mRNA.

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Ilawula ukukhiqizwa kweprotein bese ilahlwa.

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Imijovo yokugoma ye-RNA ifana nalezi zikopi eziphilayo isikhathi
esifushane zezindlela zokupheka

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zama-chromosome; kodwa ngokungafani nazo, ibangela
ukukhiqizwa kwamaprotheni angafanele emizimbeni yethu.

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Esikhundleni salokho, zibangela ukwakheka kwama-antigen
angaphandle, njengoprotheni ye-spike ye-SARS-CoV-2.

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Ukujovwa ngakunye kwalolu hlobo lwesitofu sokugoma kunikeza
amakhophi angaphezu kwebhiliyoni (izimolekyuli ze-mRNA).

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Ukukhiqizwa ngobuningi kwe-mRNA yesitofu sokugoma
kudinga ukutholakala ngobuningi kweresiphi ye-DNA.

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Lokhu kungenziwa kanjani?

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Indlela esetshenziselwa ukuxazulula le
nkinga iyisisekelo sobunjiniyela bezakhi zofuzo.

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Amabhiliyoni namatriliyoni wekhophi
yezindlela zokupheka ze-DNA avela kubaktheriya.

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Izindlela zokupheka zifakwe kuma-chromosome amancane
abakhiqizwa amabhaktheriya abizwa ngokuthi ama-plasmid.

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Amaseli abakhohlela angahlukana njalo
ngemizuzu engu-20, okusho ukuthi inani lawo liyanda

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izikhathi eziyisishiyagalombili ngehora ngalinye.

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Ngale ndlela, amagciwane angenakubalwa angathola ekukhuleni
oketshezi ezinsukwini ezimbalwa kuphela, futhi iseli ngalinye

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legciwane lizoba nezikopi eziningi zeplasmid okukhulunywa ngayo.

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Ama-plasmidi kulula ukuwaguqula.

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Ama-recipe angaphandle, okungukuthi amagene
akhoda amaprotheni e-virus, isibonelo, angafakwa.

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Ngemva kokwanda kwamabhaktheriya, ama-plasmidi aqoqwa bese
esetshenziswa njengamathayiphu ekukhiqizeni amakhophi e-mRNA.

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Ekugcineni, ama-RNA afakwa emagobulini amancane kakhulu
kawoyela abizwa ngokuthi ama-lipid nanoparticles (LNPs).

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Izithako eziyinhloko ze-LNP zikhiqizwa
ngokwenziwa futhi zaziwa ukuthi ziyingozi ngokwazo.

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Ngaphezu kwalokho, ama-lipid compounds akhethekile asetshenziswa
yi-Pfizer/BioNTech ne-Moderna awazange ahlolwe ngisho

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emuntwini ngaphambi kokuba imijovo ye-mRNA evela
kubakhiqizi bobabili ithole imvume yezimo eziphuthumayo.

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Lokhu kubeka ingozi yezempilo
engaphikeki futhi engadingekile ngokuphelele.

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Ukupakishwa kwe-RNA yi-LNP kuyivikela ekubhujisweni, kuvumela
ukuthi ifinyelele kuzo zonke izitho zomzimba ngokugeleza kwegazi.

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Lapho, ama-LNP aziphatha njengezimbhamu zaseTroja.

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Ziyamuncwa yizicubu zeseli, kanti i-mRNA ikhululwa.

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Lokhu kulandelwa ukukhiqizwa kweprotein ye-spike.

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Lokhu-ke kubangela impendulo yokuzivikela
komzimba, kuhlanganisa nokwakheka kwamabhowuni okuvikela

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athile akhelwe ukusivikela ekuthelelekeni esizayo.

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Nokho, uhlelo lokuzivikela komzimba lubona futhi
lubhubhise amaseli omzimba akhiqiza amaprotheni angaphandle.

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Ngokwemvelo, lokhu kwenzeka lapho
amaseli ethu ethathelwa amagciwane.

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Lokhu ikhono lokubona amaprotheni
angaphandle njengalokhu sekukhona ekuzalweni.

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Kusivikela kuyo yonke impilo yethu, njengoba amaseli
agcwele amagciwane ebulawa ngempumelelo ngale ndlela.

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Ayikwazi ukucindezelwa.

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Ngakho-ke, lapho i-mRNA ebhala iphrotheni yangaphandle ifakwa
eselini, leso seli hlaselwa yisistimu yokuzivikela komzimba.

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Ukuphikiswa kwamalungu adluliselwe
kumzimba kubonisa leli qiniso eliyisisekelo.

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Uma wamukela isitho sami sezinso, uzosiphika.

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Uthola i-kidney yami yesibili, futhi ukwenqatshwa kwesibili
kulandela, kodwa kulokhu ngokushesha nangokucasuka okukhulu.

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Imigomo efanayo isuselwa ekwandeni okuqhubekayo
kwemiphumela eyingozi yokugonywa okuphindaphindiwe.

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Inani lekhopi ze-RNA ezipakishwe ku-LNP
ezinikezwa ngesijovo ngasinye likhulu kakhulu.

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Izinkulungwane eziningi zamangqamuzana emzimbeni
wonke zizohlaselwa yisistimu yethu yokuzivikela komzimba.

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Lolu hlaselo lungavinjwa kuphela uma
ukukhiqizwa kweprotein yangaphandle sekumisiwe.

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Kodwa lokhu kuzohlala isikhathi esingakanani?

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Kusele izinsuku ezimbalwa nje, njengoba
abakhiqizi bemithi yokugoma kanye

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neziphathimandla zokulawula beqhubeka besiqinisekisa?

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Eminyakeni emibili edlule, kwenziwe
ukubonwa okusabisa okungahambisani naleli cala.

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Kubantu abagonyiwe, iphrotheni ye-spike nokuvuvukala kwatholakala
ezithweni eziningi emavikini noma

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ezinyangeni eziningana emva kokugonywa ,
okuhlotshaniswa nezifo ezinzima futhi ezivame ukubulala.

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Kodwa-ke, le ngokukhiqizwa okuqhubekayo okungalindelekile
kweproteini ebhalwe ku-mRNA kungachazwa kanjani?

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Impendulo ekholisayo kodwa esabisa inikezwe ukutholakala
okwenziwe uMcKernan nozakwabo, abakushicilele unyaka owedlule.

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Sasivele sixoxe ngokuthi i-mRNA yakhiwa kusuka kwizifanekiso
ze-DNA ye-plasmid ngesikhathi sokukhiqizwa kwemijovo yokugoma.

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Ngaphambi kokuthi i-mRNA ipakishwe
ku-LNP, le DNA kumele kuqala isuswe.

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Ngaphandle kwalokho, i-DNA yeplasmid
ingavalelwa ema-globule we-lipid kanye ne-RNA.

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UMcKernan wathola ukuthi lesi sinyathelo esibalulekile
sokukhipha i-DNA yeplasmid besingazange senziwe ngokucophelela.

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Kutholakale inani elikhulu ngokweqile le-DNA yeplasmid
ezigabeni eziningi zamavaksini ka-Pfizer no-Moderna.

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Okuqwashisiwe nguKevin McKernan kwancishiswa
ukubaluleka ngabantu abaningi abajwayelekile.

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Iziphathimandla zokulawula zathi abakhiqizi babazise ngokuba khona
kwe-DNA; nokho, lokhu akuzange kubavimbe ekunikezeni imvume,

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njengoba amanani abikiwe ayengaphansi kwemingcele ebekwe yi-WHO.

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Kodwa le mikhawulo ivela kuphi?

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I-European Medicines Agency (EMA) ibeke umkhawulo
wama-nanogramu ayi-10 e-DNA ngedosi ngayinye yesitofu sokugoma.

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Wabhekisela embikweni we-WHO wango-1998.

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Lombiko lobuchwepheshe lithi: "Ngokwazi okwamanje,
i-DNA evela emigqeni yamaseli eqhubekayo kuze kufike ku-10

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ng ngedosi ehlanzwe manje ingabhekwa njengemukelekile."

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Umkhawulo omusha ophezulu awusebenzi
emikhiqizweni etholakala kumaseli amagciwane, emigqeni

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yamaseli e-diploid noma ekukhuleni kokuqala kwamaseli.

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Sibona ukuthi umbiko we-WHO uhlukanisa izinhlobo ezimbili ze-DNA.

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Okunye kubhekwa njengokuyingozi kakhulu kunokunye,
ngakho-ke inani lazo linqunyelwe kwinani elibekiwe.

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Kodwa i-DNA yeplasmid equkethwe emajabini e-mRNA
ingabe ingaphansi kwesiphi kwalezi zinhlobo

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ezimbili – esiyingozi kakhulu noma esingeyingozi kangako?

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Akusona ngempela isigaba kunoma yikuphi, ngoba umhlahlandlela
we-WHO ngokungaqondile ucabanga ukuthi noma yiluphi i-DNA

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olusezimweni zokwelapha noma emjovweni aluyona enye
into ngaphandle kwalokhu: i-DNA "evulekile", ukwamukelwa

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kwayo ezicubeni zomzimba wethu kuzoba buphansi kakhulu.

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Ngokuphambene nalokho, i-DNA engcolisayo
emijovweni izopakishwa nge-LNP, njengokufana ne-mRNA.

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Lokhu kuhlanganiswa kuholela ekutholeni i-DNA
ngokushesha nangempumelelo kakhulu emaselini omzimba wethu .

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Ngakho-ke bekuyodingeka ukunquma umkhawulo
"ophephile" we-DNA ehlanganiswe ne-LNP

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kusetshenziswa izivivinyo ezintsha ezihlelwe ngokucophelela.

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Kodwa ake sithathe ukuthi umkhawulo osethwe yi-EMA uyamukeleka.

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Lokhu kusiholela kuphi?

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Embikweni wayo owishiwe ngenhla , i-EMA ithi zonke izibonelo
zezitofu zokugoma eyazithola ku-Pfizer/BioNTech ngaphambi

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kokuvunywa zazihambisana nomkhawulo we-EMA we-DNA eseleyo.

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Nokho, kuyabonakala ukuthi i-EMA ayiqinisekisanga ukulawulwa
kwekhwalithi okuqhubekayo ngemva kokuvunywa, futhi lokhu kuyafana

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nakuzo zonke ezinye iziphathimandla zokulawula emhlabeni wonke.

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Lokhu kungaqedwa ngokwezitholi zikaKevin McKernan,
ngokwezitholi zakhe okuqukethwe kwe-DNA kuwo wonke amaqoqo

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omjovo oviviniwe kudlula umkhawulo obekwe yi-WHO ne-EMA.

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Lokhu kusiholela ekuqapheliseni okumangalisayo nokwesabekayo
kokuthi lezi zitozo eziyingozi zakhiqizwa ngaphandle kwanoma

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yiluphi uhlobo lokulawula, nokuthi izigidi
ezingamakhulu zabantu zafakwa ngamaqoqo

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ezitozo eziphule ngokwedlulele izimo zokuvunywa.

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Manje sekuvinjelwe ukufaka umuthi
ongahambisani nezincazelo ezibekiwe emvume yokumaketha.

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Ngakho-ke ukuqhubeka nokufakwa kwalezi zitozo
akuyona into engaphansi kwesenzo sobugebengu.

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Nansi indlela iziphathimandla zethu ezifike kuyo
ekungazini kwazo okudabukisayo, ukuthi zenze lokhu

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kubantu bazo futhi ziyaqhubeka nokwenza kanjalo.

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Qaphela: Iziphathimandla ezifanele emazweni
aseNtshonalanga ziye zanqaba ngokusebenzayo

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ukuphenya ukuthi iqembu likaMcKernan lingaba nelungelo.

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Kunalokho, bayacula ngokuvumelana bathi:
i-DNA ngeke ngisho ifinyelele emaselini.

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Futhi uma kwenzeka njalo,
kuzoshwabana ngokushesha futhi kubhujiswe lapho.

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Ngaphezu kwalokho, inhliziyo yeseli ihlukaniswe ne-cytosol yeseli
ngembambo engangeneki, ngakho-ke i-DNA yangaphandle ayikwazi

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ukungena ngaphakathi kwayo ukuze yenze umsebenzi wayo lapho.

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Okukodwa okuhle ngaleli bali elimbi kakhulu
wukuthi iziphathimandla ezibhekele manje seziziveze.

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Sebephakathi kwesimo esinzima kakhulu,
futhi lokhu kuyabonakala kubo bonke.

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Izikhungo zikahulumeni ngokusobala
zihlangene nabenzi baleli cala elesabekayo.

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Okutholakele kukaMcKernan kumele kudale ukukhathazeka
kunoma ubani onolwazi oluncane nje lwezinto eziphilayo.

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Kuyacaca ukuthi i-DNA yeplasmid ephakishwe nge-LNP
izongena kumaseli ethu ngokuphumelela okuphezulu.

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Umembrane wenyukliya awukwazi ukuvikela ama-chromosome
ngokuqhubekayo; uyanyibilika ngesikhathi sokwahlukaniswa

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kweseli ngasinye, bese i-DNA engajwayelekile ifakwa
ezinukleiyini ezisanda kwakhiwa zamangqamuzana amadodakazi.

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Lokhu ukuthathwa kuphela kwanele ukuqalisa
ukukhiqizwa kwesikhathi eside kwamaprotheni abhalwe ikhodi –

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akudingeki ukuhlanganiswa ku-DNA yamakhromosomu ethu .

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Ngakolunye uhlangothi, uma ukubumbana
okunjalo kwenzeka, kuletha izingozi ezengeziwe.

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Imiphumela kaMcKernan isiqinisekisiwe
yilabhorethri eziningi e-United States naseCanada.

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Manje sibika ngeminye imivivinyo eyenziwe yiqembu labacwaningi
baseJalimane abanamava kumabhetshi omuthi wokugoma we-BioNTech.

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Umphumela wokuqala: Njengangaphambilini,
izilinganiso ezinkulu ze-DNA yamagciwane

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zatholakala kuzo zonke iziqephu eziyisithupha ezihlolwe.

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Zonke izakhi zofuzo ezazitholwe ngaphambilini
nguMcKernan ku-plasmid ziye zahlonishwa lapha futhi.

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Lokhu futhi kusebenza ku-promoter ebizwa
nge-SV40, ingxenye ekhethekile kakhulu ukuba khona kwayo

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kwakufihlwe emphakathini nakubaphathi bokulawula.

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Kungani i-Pfizer ne-BioNTech zafaka i-promoter
ye-SV40 ku-plasmid yazo kuyindaba ethakazelisayo kakhulu.

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Le ngxenye ayidingeki ekukhiqizweni kwe-mRNA
ye-spike, futhi ayikakabi khona ku-plasmid

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esetshenziswa yiModerna ekukhiqizweni kwemithi yokugoma.

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Nokho, i-promoter ye-SV40 inekhono elimangalisayo lokuzifihla
nokudlula, kanye nezilandelwano ze-DNA ezixhunyiwe

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kuyo, ngokusebenzisa ingubo yenukleasi
engaphazamisekile, ngisho nangamaseli angahlukanisi okwamanje.

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Siyakushiya ukuthi ucabange ukuthi lokho kusho ukuthini.

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Umbuzo olandelayo: Ingabe i-DNA yeplasmidi ingangeniswa
emaseluleni abantu futhi ihlale khona isikhathi eside?

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Impendulo ithi yebo!

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Ithimba locwaningo lathola ukuthi ukwamukelwa kwe-DNA kwenzeka
ngokushesha futhi kuhlala emaselini izinsuku

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eziningi kamuva, kusengatholakala ngisho
nangemva komjikelezo wokwahlukaniswa kwamaseli.

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Isimangalo sokuthi i-DNA edliwe iyabhujiswa
ngokushesha ngaleyo ndlela siyinkohliso

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ngokuphelele – siyimibiko yezokwelapha eyingozi.

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Manje sekunezibonelo eziningi zokufakwa
kwe-DNA yangaphandle encwadini yokuphila

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nasemakhromozomeni wamaseli nezilwane zaselebhorethri.

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Imiphumela engase ibe khona iningi futhi ayibikezeleki.

18:36.600 --> 18:46.293
Ukuphazamiseka ohlelweni olulungiselelwe kahle olulawula
ukuhlukana kwamaseli nokuthuthukiswa kungaholela kumdlavuza.

18:46.293 --> 18:53.650
Izinguquko kumagene asebenza njengengxenye yohlelo lokuzivikela
komzimba zingaholela ekusebenzeni kwalo okungeyikho.

18:53.650 --> 19:03.420
Ukuphazamiseka kwamagene kumaseli obuchopho
kungabangela noma yisiphi isifo sobuchopho esingacabangeka.

19:03.420 --> 19:12.343
Uma i-DNA yangaphandle ifaka yona ngokwayo
kuma-chromosome e-sperm noma kumaqanda agcotshiwe, izimpawu

19:12.343 --> 19:18.340
eziguquliwe ezivela ngaleyo ndlela zizodluliselwa.

19:18.340 --> 19:21.798
Lokhu kusiholela embuzweni wethu wokugcina:

19:24.732 --> 19:35.400
Kufanele sikhathazeke yini ukuthi i-DNA yamagciwane
evela emijoweni ingafakwa nakuma-chromosome abantu?

19:35.400 --> 19:44.522
Ukuze kucaciswe lo mbuzo, ithimba laseJalimane lathumela
izitshalo zamangqamuzana ezitshelwe umuthi wokugoma

19:44.522 --> 19:50.849
kuKevin, licela ukuhlelwa okuphelele kwe-DNA yala mangqamuzana.

19:50.849 --> 19:56.254
Imiphumela ingabukwa ku-Substack kaKevin .

19:56.254 --> 20:00.620
Impendulo futhi: yebo!

20:00.620 --> 20:11.267
Ubufakazi be-DNA yamagciwane kumakhromozomu
wale seli seluseduze nokuphelela okwamanje.

20:11.267 --> 20:23.426
Uma lokhu kwenzeka kumaseli azimele, ngabe ikhona yini imbangela
ecacile yokuthi kungani kungafanele kwenzeke nasemzimbeni?

20:23.426 --> 20:29.112
Ngalesi sikhathi, futhi kuphela
ngalesi sikhathi, impendulo yethu ithi cha.

20:29.112 --> 20:38.940
Namuhla, lapha manje, sibhekene nokuqaphela ukuthi ohulumeni
emhlabeni wonke sebengene ohlelweni lobusathane

20:38.940 --> 20:49.760
olulimaze, lubulale futhi lulungise ngokwezofuzo
izigidi zabantu abangathathi ngezinhle emhlabeni wonke.

20:49.760 --> 20:59.228
Futhi lolu hlelo luhlelelwe ukwandiswa; i-WHO
ihlose ukushintsha imijovo evamile kwezokwelapha

20:59.228 --> 21:06.227
kwabantu nakwezilwane ngemijovo ye-mRNA kuyo yonke indawo.

21:06.227 --> 21:13.863
I-WHO isitshela ukuthi imijovo yokugoma ye-COVID iveze ukuphepha
kwayo ngendlela emangalisayo kangangokuthi

21:13.863 --> 21:21.568
ukuhlolwa okujulile kwemijovo ezayo ye-mRNA
ukuze kuqhathaniswe nezinye izifo akusadingeki.

21:21.568 --> 21:31.812
Kodwa akukho okungaphambene ngeqiniso kunalesi simemezelo
esidabukisayo sokubhujiswa kwezimali ngesayensi yezokwelapha.

21:31.812 --> 21:41.020
Bafowethu nodadewethu, ngenxa yenu
nangezithandwa zenu, ningasoze nikhohlwe le nto eyodwa:

21:41.020 --> 21:47.318
Ukuvezwa kwe-antigen yangaphandle eselini
lomzimba wethu kuzoholela njalo ekuhlaselweni

21:47.318 --> 21:51.795
kwalelo seli yisistimu yethu yokuzivikela komzimba.

21:51.795 --> 21:59.673
Njengoba umuthi wokugoma omusha ngamunye we-mRNA uqukethe
i-antigen yawo yangaphandle, ngamunye wabo naye

21:59.673 --> 22:10.000
uzobangela umonakalo, njengoba sesikubonile ngemithi yokugoma
eyakhiwe ngokufakelwa izakhi zofuzo yokulwa ne-COVID-19.

22:10.000 --> 22:17.609
Futhi njengangaphambilini, umonakalo lo
uzoba mubi kakhulu njalo lapho kuvuselelwa.

22:17.609 --> 22:27.175
Ukungcoliswa kwemijovo ye-mRNA nakho kungenzeka kakhulu kube
yinto evamile, ngoba akukho indlela eshibhile nephumelelayo

22:27.175 --> 22:36.581
yokuhlukanisa ngokuthembekile i-mRNA ekhiqizwa ngobuningi
kuma-plasmid – futhi noma kunjalo, kubonakala kungekho muntu

22:36.581 --> 22:43.051
oqapha ukuhambisana nanoma yiziphi izindinganiso zokukhiqiza.

22:43.051 --> 22:45.860
Uhlelo lwe-WHO luyisongelo kubantu bonke.

22:45.860 --> 22:49.346
Kuyasongela WENA nabathandekayo bakho.

22:49.346 --> 22:56.453
Bantu bomhlaba wonke, nihlangane
nisindise kulesi buhlanya bobugebengu!

22:56.453 --> 23:03.890
Masiyeke imijovo ye-mRNA – masiyeke i-WHO!

23:13.921 --> 23:19.759
Sawubona, igama lami nginguLara
futhi namuhla ngizokutshela indaba yami.

23:19.759 --> 23:21.290
Igama lami nginguLara.

23:21.290 --> 23:24.848
Igama lami nginguLara, futhi ngagubha
iminyaka engamashumi amabili ngenyanga edlule.

23:24.848 --> 23:29.975
Igama lami nginguLara, ngineminyaka engamashumi
amabili, futhi emasontweni amabili ngaphambi kokugubha

23:29.975 --> 23:34.063
iminyaka yami engu-18, ngazithola ngingakwazi ukuhamba.

23:34.063 --> 23:42.942
Ezinsukwini ezintathu ngemva kokuthola umjovo wami wesithathu
we-coronavirus ngomhlaka 17 Januwari 2022, ngahlehlela phansi,

23:42.942 --> 23:52.431
futhi lapho ngivuka ngangididekile ngokuphelele futhi imilenze
yami yayingasakwazi ukungisekela. Angisakwazanga ukuhamba.

23:52.431 --> 23:55.931
Angisoze ngikhohlwe lolu suku kungekudala.

23:55.931 --> 24:03.188
Emva kwehora, nami ngaqala ukuba nobunzima
bokuphefumula, kwathi-ke ngalethelwa esibhedlela sezinsana.

24:03.188 --> 24:05.063
Yebo.

24:07.345 --> 24:12.260
Esikhathini esilandelayo, isimo sami asizange sishintshe kakhulu.

24:12.260 --> 24:15.758
Ngisho nezandla zami bezingakwazi ukubamba izinto kahle.

24:15.758 --> 24:18.243
Ngichithe izinsuku zami embhedeni.

24:18.243 --> 24:22.491
Ukufunda kwakungekho okwenzekayo ngoba
ngesikhathi ngifika egameni lesithathu esivakweni,

24:22.491 --> 24:25.149
bengisele ngikhohliwe amagama amabili okuqala.

24:26.657 --> 24:30.092
Umculo namavidiyo kwangigcina ngingedwa.

24:30.092 --> 24:35.217
Ukungakwazi ukubamba ukuchama kwengezwe
kulesi sihlanganiso, igama engangingazi ngisho.

24:35.217 --> 24:39.060
Bengivaliwe embhedeni izinyanga ezine.

24:39.060 --> 24:41.451
Ngisanda ukugubha iminyaka engu-18.

24:41.451 --> 24:48.120
Kimina, bekuyoba yisikhathi sokuphuma,
sokuhlangana nabangane nokujabulela inkululeko yami.

24:48.120 --> 24:51.273
Kodwa ngangiboshwe embhedeni.

24:51.273 --> 24:54.648
Abangane bathi sala kahle ngokulandelana.

24:54.648 --> 25:02.408
Ngakolunye uhlangothi, kubuhlungu kakhulu kimi, kodwa ngakolunye
uhlangothi, kufanele wenzeni nomuntu ohlala nje ekhaya?

25:02.408 --> 25:06.135
Angikwazi ukuzichazela yonke le nselelo elandelayo.

25:06.135 --> 25:08.593
Kuzodlula lesi sikhathi.

25:08.593 --> 25:12.197
Ngizochaza ngamazwi angukhiye.

25:12.197 --> 25:15.619
I-acupuncture yangibuyisela ezinyaweni zami.

25:15.619 --> 25:17.860
Ngiphinda unyaka esikoleni.

25:17.860 --> 25:23.150
Ngizoya ohambweni amabili amafushane, eParis naseRoma. Hureyi!

25:23.150 --> 25:29.096
Kodwa ngoSepthemba 2022... Ukukhathala okunzima kuyangenela.

25:29.096 --> 25:31.330
Ukuphinda wehla kuqala.

25:31.330 --> 25:33.486
Angikwazi ukuya futhi.

25:33.486 --> 25:37.273
Ngizama ukuphinda ikilasi. Akusebenzi.

25:37.273 --> 25:39.391
Ukushintsha izinhlobo zezikole, kulungile.

25:39.391 --> 25:40.953
Akusekho ikholeji lezifundo eziphakeme.

25:40.953 --> 25:42.740
Kodwa ukushintsha kuhle.

25:42.740 --> 25:48.462
Ngizothola izibambo ukuze ngikwazi ukuya
esikoleni ngisho nasezinsukwini ezimbi.

25:48.462 --> 25:54.174
Isiqala isikhathi sokuphindaphinda
kwalezo ezibizwa ngokuthi ukuphinda kugule.

25:54.174 --> 25:58.720
Izibambo azisangisizi ngoba
sengikhathele kakhulu ukuze ngizisebenzise.

25:58.720 --> 26:04.727
Kumele ngamukele lokho
engangingakufuni nhlobo: isihlalo esinamavili.

26:04.727 --> 26:06.965
Kodwa ngiyakwazi ukuya esikoleni.

26:06.965 --> 26:10.987
Khona-ke ngangiphila ohlelweni oluthile lokuphindaphinda.

26:10.987 --> 26:14.404
Manje sengifunde ukuphila nalezi zokuphindaphinda.

26:14.404 --> 26:20.075
Kusukela ngalelo langa ngoJanuwari 2022,
impilo yami ibe sengathi iyirola-kosteri:

26:20.075 --> 26:26.948
Ukuphinda wehla, ukumisa, ukuphinda wehla
okungaphelele, ukumisa, ukuphinda wehla okukhulu, ukumisa.

26:26.948 --> 26:31.335
Akulula. Kodwa ngiyakwazi ukukwenza. Ngifuna ukukwenza.

26:31.335 --> 26:33.862
Nginephupho eziningi.

26:33.862 --> 26:40.086
Phakathi nale minyaka emibili, bengihlale ngigxile
kakhulu entweni engase ibonakale ingabalulekile.

26:40.086 --> 26:42.134
Angizange ngazi ukuthi nganginalo ini.

26:42.134 --> 26:43.959
Akekho owaziyo.

26:43.959 --> 26:50.290
Ngiyakhumbula usuku lapho umama wami ethola
ku-inthanethi ukuthi isifo sami esingenaleli gama sasinalo igama

26:50.290 --> 26:53.880
ekugcineni: i-Post-Vac Syndrome, i-Post-Vac Syndrome.

26:53.880 --> 26:58.335
Manje ngiyakwazi ukuhleka ngalokho.
Ngoba empeleni akuyona igama lesifo.

26:58.335 --> 27:00.020
Kodwa ngangijabule.

27:00.020 --> 27:02.638
Manje sengiyazi ukuthi kwakubaluleke kangakanani kimi.

27:02.638 --> 27:08.300
Ngoba othile wangibona
ngokuzumayo. Futhi isimo sami sasinesibizo.

27:08.300 --> 27:11.537
Ngoba ngabelane nabanye ngesifo sami.

27:11.537 --> 27:13.312
Angisekho ngedwa.

27:13.312 --> 27:15.946
Futhi kwakukhulula.

27:15.946 --> 27:23.319
Ngemva kokuhlolwa okuningi, okwagcina njalo kusho
ukuthi "konke kujwayelekile," ekugcineni ngithole ukuxilongwa

27:23.319 --> 27:27.934
okubili: i-small fibre neuropathy nesifo sokukhathala.

27:27.934 --> 27:34.200
Kulo hambo olude, angikaze ngibe
nezipiliyoni ezimbi kuphela ngokunakekelwa kwezempilo.

27:34.200 --> 27:36.580
Odokotela abambalwa benza izinqumo ngokuqinile.

27:36.580 --> 27:41.752
Ungisizile ukuthi ngenze intuthuko encane,
futhi ngiyakubonga ngokujulile enhliziyweni yami.

27:41.752 --> 27:43.873
Ngisaseshashalazini.

27:43.873 --> 27:45.780
Akukapheli.

27:45.780 --> 27:47.700
Kodwa manje sekuyisicaba.

27:47.700 --> 27:49.003
Ngiyethemba ukuthi kuzohlala kunjalo.

27:49.003 --> 27:53.264
Futhi ngithemba ukuthi ngelinye ilanga
ngizokwazi ukuphuma ngokuphelele kule rollercoaster.

27:53.264 --> 27:58.699
Kuzoba kuhle ukuma phansi ngemilenze yami esebenzayo.

27:58.699 --> 28:00.730
Qhubeka nocwaningo!

28:00.730 --> 28:08.476
Sonke sidinga umbono. Futhi ngiyakudinga. Ngiyabonga.

28:11.867 --> 28:17.098
Inhlangano ye-MWGFD iye yenza ezinye izingxoxo ezimangalisayo
nezithinta inhliziyo nabantu abalimele

28:17.098 --> 28:22.273
ngemijovo ye-mRNA ochungechungeni olubizwa
ngokuthi "abagonyiwe, balimele, banqatshelwe".

28:22.273 --> 28:25.740
Ungazithola lezi ngaphansi kwesixhumanisi esiboniswe.

28:25.740 --> 28:32.285
Njengoba ubuchwepheshe be-mRNA buzophinde bungezwe kwezinye
izitozo – noma, ngokunembile, ekwelashweni kwezofuzo

28:32.285 --> 28:39.118
– kubaluleke kakhulu ukwazisa umphakathi ngale mibiko
emangalisayo yokulimala okubangelwa umuthi wokugoma.

28:39.118 --> 28:42.797
Sicela uzizwe ukhululekile ukwabelana ngalezi zingxoxo.

28:42.797 --> 28:50.087
Ungasiza futhi ukuveza ububanzi bomonakalo
obubangelwa yimijovo ye-mRNA ngokubika noma yimuphi

28:50.087 --> 28:54.120
umonakalo wemijovo endaweni yakho ku-vetopedia.org.