Gesundheit (Polska)
Inżynieria genetyczna: zmiany genetyczne kosztem zdrowia?
16.06.2022
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Inżynieria genetyczna: zmiany genetyczne kosztem zdrowia?
Tak zwane nożyce genowe – CRISPR/Cas – są wykorzystywane w badaniach inżynierii genetycznej od 2012 roku. Umożliwiło to po raz pierwszy skorygowanie wad genetycznych w ludzkich embrionach w 2015 roku. Jednocześnie jednak zaobserwowano zmiany strukturalne w DNA istot żywych, które zostały przekazane. Czy jest to krok w rozwoju badań, czy koszmar dla historii ludzkości?
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Inżynieria genetyczna: zmiany genetyczne kosztem zdrowia?
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16.06.2022 | www.kla.tv/22818
Nowa metoda, znana jako nożyce genowe CRISPR/Cas, jest stosowana w inżynierii genetycznej od 2012 roku. Dzięki tej technologii można modyfikować materiał genetyczny istot żywych. W 2015 roku naukowcy po raz pierwszy skorygowali defekt genetyczny w ludzkich embrionach. Badanie przeprowadzone przez Uniwersytet w Uppsali pokazuje, że ta powierzchownie obiecująca metoda nie jest pozbawiona niebezpieczeństw. Zespół naukowy odkrył, że CRISPR/Cas może powodować duże zmiany strukturalne w DNA danio pręgowanego. Dzięki tej metodzie genom, czyli materiał genetyczny, można „rozciąć” oraz wstawić lub usunąć skrawki DNA. Ale nożyczki genowe mogą również wcinać się w genom w w niepożądanych miejscach. W trakcie tego procesu niepożądane zmiany są również przekazywane potomstwu ryb zebraficznych. Najnowsze badania potwierdzają zatem starsze doniesienia, które wskazywały na niezamierzone skutki tej procedury inżynierii genetycznej. Ten „postęp naukowy” otworzyłby wrota dla celów „ulepszania” genetycznego człowieka i mógłby w ten sposób mieć nieprzewidywalne, destrukcyjne skutki dla ludzkości, ale także dla innych żywych istot i środowiska. Czy tego chcemy?
von pr. /sak.
(Nr. 117, S.12) https://ueaeprints.uea.ac.uk/id/eprint/65894/
https://www.testbiotech.org/aktuelles/unbeabsichtigte-veraenderungen-durch-crisprcas-zeigen-neuartige-risiken
https://www.biorxiv.org/content/10.1101/2021.10.05.463186v1